Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
Injury Severity Score Precision for Determining Undertriage in Trauma Consultation Patients: A Retrospective Study. [PDF]
Dunham CM +3 more
europepmc +1 more source
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III +7 more
wiley +1 more source
Evaluation of emergency department admissions of mass casualty patients using the revised trauma score, injury severity score, and trauma and injury severity score. [PDF]
Karaca B +3 more
europepmc +1 more source
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee +10 more
wiley +1 more source
Comparison of the Thoracic Trauma Severity Score (TTSS) and Trauma and Injury Severity Score (TRISS) in predicting clinical outcomes in chest trauma patients: protocol for a prospective cohort study from Iraq. [PDF]
Khamees AR +9 more
europepmc +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Correction: Mizuochi et al. Patients with Severe Trauma Having an Injury Severity Score of 24 and above Develop Nutritional Disorders. <i>Diagnostics</i> 2024, <i>14</i>, 1307. [PDF]
Mizuochi M +3 more
europepmc +1 more source
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez +6 more
wiley +1 more source

