Results 241 to 250 of about 556,518 (293)

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

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Maxillofacial Injury Severity Score: proposal of a new scoring system

International Journal of Oral and Maxillofacial Surgery, 2006
In this study a new injury severity score system, the Maxillofacial Injury Severity Score (MFISS), was developed to evaluate the characteristics of injury from maxillofacial trauma. Nine hundred and two cases of maxillofacial trauma were included in this study to evaluate injury severity using the MFISS, which was designed on the basis of Abbreviated ...
J, Zhang, Y, Zhang, M, El-Maaytah, L, Ma, L, Liu, L D, Zhou   +5 more
exaly   +3 more sources

Comparison of the New Injury Severity Score and the Injury Severity Score

The Journal of Trauma: Injury, Infection, and Critical Care, 2004
The New Injury Severity Score (NISS) was proposed in 1997 to replace the Injury Severity Score (ISS) because it is more sensitive for mortality. We aim to test whether this is true in our patients.This study was a retrospective review of data from 6,231 consecutive patients over 3 years in the trauma registry of a Level I trauma center studying outcome,
Seow-Yian, Tay, Edward P, Sloan, Leslie, Zun, Philip, Zaret   +3 more
openaire   +2 more sources

THE INJURY SEVERITY SCORE

The Journal of Trauma: Injury, Infection, and Critical Care, 1976
THE INJURY SEVERITY SCORE: AN UPDATE SUSAN BAKER;BRIAN O'NEILL; The Journal of Trauma: Injury, Infection, and Critical ...
S P, Baker, B, O'Neill
openaire   +2 more sources

Injury Severity Score versus New Injury Severity Score for Penetrating Injuries

Prehospital and Disaster Medicine, 2002
AbstractIntroduction:The New Injury Severity Score (NISS) was introduced in 1997 to improve outcome prediction based on anatomical severity scoring in trauma victims. Studies on populations of blunt trauma victims indicate that the NISS, predicts better than the Injury Severity Score (ISS) mortality post-injury, which is why the NISS has been ...
Hans, Husum, Gino, Strada
openaire   +2 more sources

The Injury Severity Score Revisited

The Journal of Trauma: Injury, Infection, and Critical Care, 1988
The injury severity score (5) (iss) is a scalar (single number) measure of anatomic injury, widely used in and an important contribution to trauma research. The iss is the sum of squares of the highest abbreviated injury scale (1-3) (AIS) grade in each of the three most severely injured body regions.
W S, Copes, H R, Champion, W J, Sacco, M M, Lawnick, S L, Keast, L W, Bain   +5 more
openaire   +2 more sources

Advances in Injury Severity Scoring

Journal of Emergency Nursing, 2007
Carla P. Rennie is a Trauma Program Manager, Stamford Hospital Department of Surgery, Stamford, Conn. Paula Brady is a Surgical Research Assistant, Stamford Hospital Department of Surgery, Stamford, Conn. For correspondence, write to: Carla P. Rennie, RN, MSN, Trauma Program Manager, Stamford Hospital Department of Surgery, 30 Shelburne Road, Stamford,
Carla P, Rennie, Paula C, Brady
openaire   +2 more sources

New Injury Severity Score and Trauma Injury Severity Score are superior in predicting trauma mortality

Journal of Trauma and Acute Care Surgery, 2021
BACKGROUND Trauma scores are used to give clinicians appropriate quantitative context in making decisions. Studies show that anatomical trauma scores predicted intensive care unit admission better, while physiological trauma scores predicted mortality better.
Magnus, Chun, Yichi, Zhang, Chad, Becnel, Tommy, Brown, Mohamed, Hussein, Eman, Toraih, Sharven, Taghavi, Chrissy, Guidry, Juan, Duchesne, Rebecca, Schroll, Patrick, McGrew   +10 more
openaire   +2 more sources

Abbreviated Injury Scale and Injury Severity Score

The Journal of Trauma: Injury, Infection, and Critical Care, 1985
The Abbreviated Injury Scale and the Injury Severity Score are important tools for grading the severity of injury to trauma patients. The Trauma Chart provided is a simple and concise guide for scoring and recording this useful information. The chart is useful in both a large wall-mounted form and in the reduced two-page form included in this article.
L, Greenspan, B A, McLellan, H, Greig
openaire   +2 more sources