Results 81 to 90 of about 556,518 (293)

Neuropsychological evaluation of blast-related concussion: Illustrating the challenges and complexities through OEF/OIF case studies [PDF]

, 2011
Background/objective: Soldiers of Operations Enduring Freedom (OEF) and Iraqi Freedom (OIF) sustain blast-related mild traumatic brain injury (concussion) with alarming regularity. This study discusses factors in addition to concussion, such as co-morbid
Charlesworth, Molly J, Ferrier-Auerbach, Amanda G, Hoelzle, James B, McGuire, Kathryn A., Nelson, Nathaniel W, Sponheim, Scott R   +5 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Modelling the disability severity score in motor insurance claims: an application to the Spanish case [PDF]

, 2015
Bodily injury claims have the greatest impact on the claim costs of motor insurance companies. The disability severity of motor claims is assessed in numerous European countries by means of score systems. In this paper a zero inflated generalized Poisson
Boucher, Jean-Philippe, Santolino, Miguel   +1 more
core  

Soluble triggering receptor on myeloid cells-1 is expressed in the course of non-infectious inflammation after traumatic lung contusion : a prospective cohort study [PDF]

, 2011
Introduction: The triggering receptor expressed on myeloid cells-1 (TREM-1) is known to be expressed during bacterial infections. We investigated whether TREM-1 is also expressed in non-infectious inflammation following traumatic lung contusion. Methods:
Bingold, Tobias Michael, Pullmann, Barbara, Sartorius, Sven, Geiger, Emanuel Valentin, Marzi, Ingo, Zacharowski, Kai, Wissing, Heimo, Scheller, Bertram   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparison of the different versions of the abbreviated injury scale in the assessment of isolated head trauma severity

BMC Public Health
Background Head trauma is a significant public health issue in Taiwan. This study examines the differences in medical needs and outcomes for patients with isolated head trauma scored via Taiwan’s health insurance versions of the Abbreviated Injury Scale (
Chia-Wen Chen, Yi-Syuan Wu, Tse-Lun Wang, Pei-Ling Lee, Yen‑Ko Lin, Yung-Sung Yeh, Pei-Shih Chen, Chao‑Wen Chen   +7 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Sample representation in a psychological treatment study after single event paediatric trauma [PDF]

, 2013
Children and their families who attended an emergency department following a single traumatic incident and who agreed to participate in a psychological treatment study (N = 211) were compared with nonparticipants (N = 2333) on several measures of trauma ...
Drummond, P.D., Kemp, M.
core   +1 more source

Impact of Level of Effort on the Effects of Compliance with the 3-Hour Rule [PDF]

, 2019
Objective To determine if patients’ level of effort (LOE) in therapy sessions during traumatic brain injury (TBI) rehabilitation modifies the effect of compliance with the 3-Hour Rule of the Centers for Medicare & Medicaid Services.
Beaulieu, Cynthia L., Bogner, Jennifer, Corrigan, John D., Dijkers, Marcel P., Hade, Erinn M., Hammond, Flora M., Horn, Susan D., Peng, Juan, Seel, Ronald T., Swan, Melanie, Timpson, Misti L.   +10 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source