Results 21 to 30 of about 426 (110)
Closed‐loop control is demonstrated for aerosol jet printing by integrating light scattering measurements of the aerosol stream with custom printer software. This system allows quantitative approaches to ink development and fundamental process studies, and supports more consistent and direct control of the deposition rate to support more reliable ...
Jeremy D. Rurup, Ethan B. Secor
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Abstract Givosiran, an RNA interference‐based therapeutic, is a recent addition to the limited treatment armamentarium for acute hepatic porphyria (AHP). As a small interfering RNA that is selectively taken up in the liver, both the mechanism and targeted delivery create a complex relationship between givosiran pharmacokinetics (PK) and the ...
Jongtae Lee+2 more
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A Nucleophilic Activity‐Based Probe Enables Profiling of PLP‐Dependent Enzymes
The first activity‐based probe for PLP‐dependent enzymes is reported. The trifunctional probe contains an N‐hydroxyalanine warhead, a linear diazirine, and an alkyne to enable enrichment. The essential protein LysA was identified as the primary target of the probe.
Scott I. Brody+7 more
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3D Nanolithography by Means of Lipid Ink Spreading Inhibition
Starting from a fluid phase phospholipid ink, 3D patterning is achieved using dip‐pen nanolithography. Pre‐coated Serum Albumin on the surfaces yield unprecedented phospholipid ink spreading inhibition, which enables thickness coordinate control capacity through the writing parameters, namely writing speed and relative humidity. The final metallization
Eider Berganza+7 more
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Prussian Blue: Chemistry, Commerce, and Colour in Eighteenth‐Century Paris
This essay reconsiders the story of a pigment. Prussian blue, discovered at the beginning of the eighteenth century, is often described as a revolutionary colour that instantly transformed painters’ palettes and practices. Grounded in a ‘thick description’ of the pigment's history in Paris, this article challenges the legendary account of Prussian blue
Charlotte Guichard+2 more
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Hybrid Mucin‐Vaterite Microspheres for Delivery of Proteolytic Enzyme Chymotrypsin
This study proposes hybrid microspheres made of mucin and mesoporous crystals of vaterite as the carriers for local delivery of proteases. Proteolytic activity is preserved in both pure carbonate and hybrid microspheres, being pH dependent. The modification of carbonate microspheres with mucin i) enhances retention of chymotrypsin on hybrid ...
Nadezhda G. Balabushevich+6 more
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Rapid Capture of Cancer Extracellular Vesicles by Lipid Patch Microarrays
Extracellular vesicles have great prospects as diagnostic and therapeutic tools. However, their isolation still poses challenges. A novel supported lipid‐membrane‐based platform is introduced for rapid capture, with high specificity and sensitivity, only a small needed analyte volume, and without additional purification steps.
Hui‐Yu Liu+9 more
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Abstract This paper explores the methodological aspects of a user‐led study investigating mental health service user experiences of targeted violence and abuse (often called 'hate crime'). 'Keeping Control' was a 16‐month qualitative study, undertaken in the context of adult safeguarding reforms in England.
Alison Faulkner+7 more
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Nanoscale Patterning of Carbon Nanotubes: Techniques, Applications, and Future
Carbon nanotube (CNT) devices are achieving maturity and directly competing with devices using conventional materials. However, a major challenge to fully commercialize is the scalable placement of CNTs into nanoscale patterns/architectures into macroscale devices.
Alexander Corletto, Joseph G. Shapter
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Policy Responses to Domestic Violence, the Criminalisation Thesis and ‘Learning from History’
Abstract The ‘criminalisation thesis’ has proved a contentious but defining feature of modern social and legal responses to domestic violence since the 1970s. However, criminalisation has not always been the focus of legal attempts to tackle violence or offer recourse to victims.
LUCY WILLIAMS, SANDRA WALKLATE
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