Results 11 to 20 of about 815 (127)

Distinct Effects of Complement C4A and C4B Copy Numbers in Systemic Sclerosis Serological and Clinical Subtypes. [PDF]

Arthritis Rheumatol
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. The variable copy number (CN) of C4 genes and retroviral human endogenous retrovirus K (HERV‐K) element influence its function.
Martínez-López J, Rangel-Peláez C, Rodriguez-Martin I, Guillen-Del-Castillo A, Simeón-Aznar CP, Callejas JL, Distler O, International SSc Group, PRECISESADs Clinical Consortium, Proudman SM, Nikpour M, Australian Scleroderma Interest Group (ASIG), Hunzelmann N, Moroncini G, de Vries-Bouwstra JK, Herrick AL, Allanore Y, Alarcon-Riquelme ME, Beretta L, Assassi S, Denton CP, Mayes MD, Martin J, Acosta-Herrera M, Kerick M.   +24 more
europepmc   +2 more sources

Sarilumab in Polyarticular-Course Juvenile Idiopathic Arthritis: Dose-Finding and 1-Year Analysis of a Phase 2b, Open-Label, Multicenter Study. [PDF]

Arthritis Care Res (Hoboken)
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
De Benedetti F, Penadés IC, Nikishina I, Foeldvari I, Spindler AJ, Kozlova A, Rubio-Pérez N, Quartier P, Żuber Z, Barria R, Clemente D, Cornejo GV, Marzan K, Liu N, Xu C, DiMartino S, Giannelou A, Cao-Ghoul F, Akinlade B, Baret-Cormel L.   +19 more
europepmc   +2 more sources

Long-Term Effect of Macrolides on Helicobacter pylori Eradication: Data From the European Registry on Helicobacter pylori Management (Hp-EuReg). [PDF]

Helicobacter
ABSTRACT Background and Aims Previous antibiotic use influences Helicobacter pylori antibiotic resistance. This study evaluated how prior population‐level macrolide (especially clarithromycin) use affects H. pylori eradication success in naïve patients. Methods Retrospective, multicenter, ecological study. Multivariate logistic regression was performed
Nyssen OP, Ortega GJ, Jonaitis L, Pérez-Aísa Á, Tepes B, Lucendo AJ, Tejedor-Tejada J, Bumane R, Garre A, Huguet JM, Perona M, Núñez Ó, Pabón-Carrasco M, Castro-Fernández M, Areia M, Barrio J, Loro AM, Butler TJ, Marcos MS, Keco-Huerga A, Cajal MD, Denkovski M, Pavoni M, Buzás GM, Lerang F, Losurdo G, Wolfe García PM, Phull PS, Martínez-Domínguez SJ, Kupcinskas J, Leja M, Marcos-Pinto R, Smith SM, Gasbarrini A, Papp V, Rodríguez BJG, Alonso MS, Villarroya RP, Mejide PP, Jiménez-Moreno M, Pascual-Mato M, Bravo-Pache C, Montes M, Cano-Català A, Parra P, Moreira L, Mégraud F, O'Morain C, Bujanda L, Gisbert JP, Hp‐EuReg investigators.   +50 more
europepmc   +2 more sources

Cystathionine β-Synthase Deficiency in the E-HOD Registry-Part II: Dietary and Pharmacological Treatment. [PDF]

J Inherit Metab Dis
ABSTRACT Cystathionine β‐synthase (CBS) deficiency (classical homocystinuria) has a wide range of severity. Mildly affected patients typically present as adults with thromboembolism and respond to treatment with pyridoxine. Severely affected patients usually present during childhood with learning difficulties, ectopia lentis and skeletal abnormalities;
Morris AAM, Sokolová J, Pavlíková M, Gleich F, Kölker S, Dionisi-Vici C, Baumgartner MR, Hannibal L, Blom HJ, Huemer M, Kožich V, E‐HOD Consortium.   +11 more
europepmc   +2 more sources

Improving the nutritional evaluation in head neck cancer patients using bioelectrical impedance analysis: Not only the phase angle matters. [PDF]

J Cachexia Sarcopenia Muscle
Abstract Background Malnutrition and sarcopenia are highly prevalent in patients with head neck cancer (HNC). An accurate early diagnosis is necessary for starting nutritional support, as both are clearly associated with clinical outcomes and mortality.
Herrera-Martínez AD, Prior-Sánchez I, Fernández-Soto ML, García-Olivares M, Novo-Rodríguez C, González-Pacheco M, Martínez-Ramirez MJ, Carmona-Llanos A, Jiménez-Sánchez A, Muñoz-Jiménez C, Torres-Flores F, Fernández-Jiménez R, Boughanem H, Del Galindo-Gallardo MC, Luengo-Pérez LM, Molina-Puerta MJ, García-Almeida JM.   +16 more
europepmc   +2 more sources

Should we measure quality of life among people with HIV? A multicentre survey of physicians' opinions in Spain. [PDF]

HIV Med
Abstract Objectives We assessed the opinions of physicians caring for people with HIV (PWH) from the multicentre Spanish CoRIS cohort regarding the assessment of health‐related quality of life (HRQoL). Methods We designed an online self‐administered questionnaire comprising 27 structured questions across four domains: (i) sociodemographic and clinical ...
Izquierdo R, Suárez-García I, Gómez-García T, Marco-Sánchez C, Puente-Ferreiro J, Moreno C, Diaz A, Cabello-Clotet N, Vinuesa D, Blanco JL, Melús E, Gómez-Ayerbe C, Olalla J, Riera M, Bernardino JI, de López Bernaldo de Quirós JC, Moreno S, Jarrín I, CoRIS cohort.   +18 more
europepmc   +2 more sources

Detection of clinically relevant variants in the TP53 gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL. [PDF]

Hemasphere
Abstract In chronic lymphocytic leukemia, the reliability of next‐generation sequencing (NGS) to detect TP53 variants ≤10% allelic frequency (low‐VAF) is debated. We tested the ability to detect 23 such variants in 41 different laboratories using their NGS method of choice.
Pavlova S, Malcikova J, Radova L, Bonfiglio S, Cowland JB, Brieghel C, Andersen MK, Karypidou M, Biderman B, Doubek M, Lazarian G, Rapado I, Vynck M, Porret NA, Andres M, Rosenberg D, Sahar D, Martínez-Laperche C, Buño I, Hindley A, Donaldson D, Sánchez JB, García-Marco JA, Serrano-Alcalá A, Ferrer-Lores B, Fernández-Rodriguez C, Bellosillo B, Stilgenbauer S, Tausch E, Nikdin H, Quinn F, Atkinson E, van de Corput L, Yildiz C, Bilbao-Sieyro C, Florido Y, Thiede C, Schuster C, Stoj A, Czekalska S, Chatzidimitriou A, Laidou S, Bidet A, Dussiau C, Nollet F, Piras G, Monne M, Smirnova S, Nikitin E, Sloma I, Claudel A, Largeaud L, Ysebaert L, Valk PJM, Christian A, Walewska R, Oscier D, Sebastião M, da Silva MG, Galieni P, Angelini M, Rossi D, Spina V, Matos S, Martins V, Stokłosa T, Pepek M, Baliakas P, Andreu R, Luna I, Kahre T, Murumets Ü, Pikousova T, Kurucova T, Laird S, Ward D, Alcoceba M, Balanzategui A, Scarfo L, Gandini F, Zapparoli E, Blanco A, Abrisqueta P, Rodríguez-Vicente AE, Benito R, Bravetti C, Davi F, Gameiro P, Martinez-Lopez J, Martinez-Lopez J, Tazón-Vega B, Baran-Marszak F, Davis Z, Catherwood M, Sudarikov A, Rosenquist R, Niemann CU, Stamatopoulos K, Ghia P, Pospisilova S.   +99 more
europepmc   +2 more sources

Obra en prosa sobre la veríssima inmaculada conceptió de la Mare de Déu (Valencia, Lambert Palmart, 1488): estudio material de un incunable perdido

Revista de Literatura Medieval, 2021
Este trabajo ofrece la primera descripción material de un incunable desconocido por los principales catálogos y repertorios internacionales, al haberse difundido en bibliografía de alcance muy parcial, restringida a escasos estudios filológicos de una ...
Josep Lluís Martos
doaj   +1 more source

La Inmaculada Concepción en algunas estampas de libros editados en nueva España en los siglos XVIII y XIX

UCOarte, 2017
En este artículo abordamos el estudio de unas estampas dedicadas a la Inmaculada Concepción, que ilustran unos libros publicados en Nueva España en los siglos XVIII y XIX.
Juan Isaac Calvo Portela
doaj   +1 more source

El Concejo y las fiestas de la Inmaculada de Málaga, 1640

Espacio, Tiempo y Forma. Serie IV, Historia Moderna, 1994
La fiestas en honor de la Inmaculada Concepción entroncan directamente con la tradición de la iglesia española centrada en la figura de la Virgen. Su significado, importancia y manifestaciones en la vida ciudadana están estrechamente relacionadas con el ...
Federico Fernández Basurte
doaj   +1 more source