Results 11 to 20 of about 2,488 (160)

Circadian rhythms of hosts and their gut microbiomes: Implications for animal physiology and ecology

Functional Ecology, Volume 37, Issue 3, Page 476-487, March 2023., 2023
Read the free Plain Language Summary for this article on the Journal blog. Abstract Daily light–dark cycles shape the circadian physiology and behaviour of nearly all organisms, with variation in circadian phenotypes having cascading effects on individual fitness, species interactions and species co‐evolution.
Dominik W. Schmid, Pablo Capilla‐Lasheras, Davide M. Dominoni, Nadine Müller‐Klein, Simone Sommer, Alice Risely   +5 more
wiley   +1 more source

Baseline and time‐updated factors in preclinical development of anionic dendrimers as successful anti‐HIV‐1 vaginal microbicides

WIREs Nanomedicine and Nanobiotechnology, Volume 14, Issue 3, May/June 2022., 2022
Key preclinical steps in the development of a vaginal microbicide against HIV‐1 infection to lead to clinical trials. Abstract Although a wide variety of topical microbicides provide promising in vitro and in vivo efficacy, most of them failed to prevent sexual transmission of human immunodeficiency virus type 1 (HIV‐1) in human clinical trials.
Ignacio Rodríguez‐Izquierdo, Daniel Sepúlveda‐Crespo, Jose María Lasso, Salvador Resino, Ma Ángeles Muñoz‐Fernández   +4 more
wiley   +1 more source

Evaluation of the effects of chlorhexidine digluconate with and without cBD103 or cCath against multidrug‐resistant clinical isolates of Staphylococcus pseudintermedius

Veterinary Dermatology, Volume 33, Issue 1, Page 17-e6, February 2022., 2022
Background – Because of the increased incidence of multidrug‐resistant (MDR) bacteria, the use of disinfectants over antibiotics has been encouraged. However, the interactions between disinfectants and host local immunity are poorly understood. Objective – To assess the effects of chlorhexidine digluconate (Chx), with and without selected host defence ...
Domenico Santoro, Lopamudra Kher, Vanessa Chala, Christelle Navarro   +3 more
wiley   +1 more source

Anti‐Diabetic Effects of Cucurbitacins from Ibervillea lindheimeri on Induced Mouse Diabetes

Journal of Chemistry, Volume 2022, Issue 1, 2022., 2022
Mexico has a great tradition of using medicinal plants against diabetes. For example, species from the genus Ibervillea traditionally known as “wereque” in Mexican popular medicine have a long ethnobotanical history as anti‐diabetic agents. Previous studies by our group indicated that ethyl acetate extract from Ibervillea lindheimeri (I.
Sonia E. Hernández Navia, José L. Figueroa-Hernández, José S. Rodríguez-Zavala, Miriam Rodriguez-Sosa, Mariano Martínez-Vázquez, Beatriz P. P. Oliveira   +5 more
wiley   +1 more source

Treatment of equine sarcoids using recombinant poxviruses expressing feline interleukin‐2

Veterinary Dermatology, Volume 32, Issue 3, Page 283-e77, June 2021., 2021
Background – Interleukin (IL)‐2 stimulates antitumour immunity and is successfully used for the treatment of different neoplasias. Hypothesis/Objectives –Canarypox virus locally expressing feline IL‐2 is safe and can be used to treat equine sarcoids. Conclusions –Treatment of equine sarcoids with recombinant canarypox virus expressing feline IL‐2 seems
Johanna Loschelder‐Ostrowski, Judith Christine Winter, Roswitha Merle, Robert Klopfleisch, Heidrun Gehlen   +4 more
wiley   +1 more source

Retinoic acid increases phagocytosis of myelin by macrophages

Journal of Cellular Physiology, Volume 236, Issue 5, Page 3929-3945, May 2021., 2021
We have investigated whether ligands of nuclear receptor families retinoic acid receptors, retinoid X receptors, peroxisome proliferator‐activated receptors, lipid X receptors, and farnesoid X receptors increase myelin phagocytosis by murine bone marrow–derived macrophages and Raw264.7 cells.
Siyu Wu, Lorenzo Romero‐Ramírez, Jörg Mey   +2 more
wiley   +1 more source

Circulating and Tumor-Infiltrating NK Cells From Clear Cell Renal Cell Carcinoma Patients Exhibit a Predominantly Inhibitory Phenotype Characterized by Overexpression of CD85j, CD45, CD48 and PD-1

Frontiers in Immunology, 2021
Although natural killer (NK) cells infiltrate clear cell renal cell carcinomas (ccRCC), the most frequent malignancy of the kidney, tumor progression suggests that they become dysfunctional.
Andrea Ziblat, Ximena Lucía Raffo Iraolagoitia, Sol Yanel Nuñez, Nicolás Ignacio Torres, Florencia Secchiari, Jessica Mariel Sierra, Raúl Germán Spallanzani, Agustín Rovegno, Fernando Pablo Secin, Mercedes Beatriz Fuertes, Carolina Inés Domaica, Norberto Walter Zwirner, Norberto Walter Zwirner   +12 more
doaj   +1 more source

Clinical efficacy of spray‐based heat‐treated lactobacilli in canine atopic dermatitis: a preliminary, open‐label, uncontrolled study

Veterinary Dermatology, Volume 32, Issue 2, Page 114-e23, April 2021., 2021
Background – Canine atopic dermatitis (cAD) is a common inflammatory and pruritic skin disease, with various treatment options. The use of topical products containing natural ingredients has proven increasingly popular. Objective – To evaluate the effects of a spray solution containing heat‐killed Lactobacillus rhamnosus and L. reuteri, on the clinical
Domenico Santoro, Lana Fagman, Yanping Zhang, Yu Fahong   +3 more
wiley   +1 more source

Crisis jurídica y crisis política de la inmunidad parlamentaria

Revista de las Cortes Generales, 1989
SUMARIO: I. Presentación del tema.—II. Planteamiento histórico de la inmunidad.—1. Los precedentes medievales ingleses. — 2. El modelo francés de inmunidad parlamentaria.—3.
Eloy García
doaj   +1 more source

Evaluation of the humoral response induced by BBIBP-CorV vaccine by determining neutralizing antibodies in peruvian healthcare personnel

Revista Peruana de Medicina Experimental y Salud Pública, 2021
Objective. To determine the titer of antibodies against the receptor binding domain (RBD) of the spike protein (S) in health personnel between the 4th and 12th week after receiving the BBIBP-CorV vaccine (Sinopharm). Materials and methods.
Alonso Soto, Flor de María Charca-Rodríguez, Mario Pareja-Medina, Manuel Fernandez-Navarro, Karina Altamirano-Cáceres, Elizett Sierra Chávez, Jarvis Raraz-Vidal, Nestor Cabezudo-Pillpe, Melissa Velarde-Rodríguez, Andrés Alcántara-Díaz   +9 more
doaj   +1 more source