Results 11 to 20 of about 75,298 (205)

Description of a novel adhesin of Mycobacterium avium subsp. paratuberculosis [PDF]

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
The binding and ingestion of Mycobacterium avium subsp. paratuberculosis (MAP) by host cells are fibronectin (FN) dependent. In several species of mycobacteria, a specific family of proteins allows the attachment and internalization of these bacteria by ...
Echeverria Valencia, Gabriela Fernanda   +8 more
core   +2 more sources

Performance of Colombian Silk Fibroin Hydrogels for Hyaline Cartilage Tissue Engineering

open access: yesJournal of Functional Biomaterials, 2022
The development and evaluation of scaffolds play a crucial role in the engineering of hyaline cartilage tissue. This work aims to evaluate the performance of silk fibroin hydrogels fabricated from the cocoons of the Colombian hybrid in the in vitro ...
Augusto Zuluaga-Vélez   +6 more
doaj   +1 more source

Circadian rhythms of hosts and their gut microbiomes: Implications for animal physiology and ecology

open access: yesFunctional Ecology, Volume 37, Issue 3, Page 476-487, March 2023., 2023
Read the free Plain Language Summary for this article on the Journal blog. Abstract Daily light–dark cycles shape the circadian physiology and behaviour of nearly all organisms, with variation in circadian phenotypes having cascading effects on individual fitness, species interactions and species co‐evolution.
Dominik W. Schmid   +5 more
wiley   +1 more source

Baseline and time‐updated factors in preclinical development of anionic dendrimers as successful anti‐HIV‐1 vaginal microbicides

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 14, Issue 3, May/June 2022., 2022
Key preclinical steps in the development of a vaginal microbicide against HIV‐1 infection to lead to clinical trials. Abstract Although a wide variety of topical microbicides provide promising in vitro and in vivo efficacy, most of them failed to prevent sexual transmission of human immunodeficiency virus type 1 (HIV‐1) in human clinical trials.
Ignacio Rodríguez‐Izquierdo   +4 more
wiley   +1 more source

Evaluation of the effects of chlorhexidine digluconate with and without cBD103 or cCath against multidrug‐resistant clinical isolates of Staphylococcus pseudintermedius

open access: yesVeterinary Dermatology, Volume 33, Issue 1, Page 17-e6, February 2022., 2022
Background – Because of the increased incidence of multidrug‐resistant (MDR) bacteria, the use of disinfectants over antibiotics has been encouraged. However, the interactions between disinfectants and host local immunity are poorly understood. Objective – To assess the effects of chlorhexidine digluconate (Chx), with and without selected host defence ...
Domenico Santoro   +3 more
wiley   +1 more source

Anti‐Diabetic Effects of Cucurbitacins from Ibervillea lindheimeri on Induced Mouse Diabetes

open access: yesJournal of Chemistry, Volume 2022, Issue 1, 2022., 2022
Mexico has a great tradition of using medicinal plants against diabetes. For example, species from the genus Ibervillea traditionally known as “wereque” in Mexican popular medicine have a long ethnobotanical history as anti‐diabetic agents. Previous studies by our group indicated that ethyl acetate extract from Ibervillea lindheimeri (I.
Sonia E. Hernández Navia   +5 more
wiley   +1 more source

Treatment of equine sarcoids using recombinant poxviruses expressing feline interleukin‐2

open access: yesVeterinary Dermatology, Volume 32, Issue 3, Page 283-e77, June 2021., 2021
Background – Interleukin (IL)‐2 stimulates antitumour immunity and is successfully used for the treatment of different neoplasias. Hypothesis/Objectives –Canarypox virus locally expressing feline IL‐2 is safe and can be used to treat equine sarcoids. Conclusions –Treatment of equine sarcoids with recombinant canarypox virus expressing feline IL‐2 seems
Johanna Loschelder‐Ostrowski   +4 more
wiley   +1 more source

Restoration of antitumor immunity through anti-MICA antibodies elicited with a chimeric protein

open access: yesJournal for ImmunoTherapy of Cancer, 2020
Background Natural killer and cytotoxic CD8+ T cells are major players during antitumor immunity. They express NKG2D, an activating receptor that promotes tumor elimination through recognition of the MHC class I chain-related proteins A and B (MICA and ...
Kenneth W Hance   +21 more
doaj   +1 more source

Retinoic acid increases phagocytosis of myelin by macrophages

open access: yesJournal of Cellular Physiology, Volume 236, Issue 5, Page 3929-3945, May 2021., 2021
We have investigated whether ligands of nuclear receptor families retinoic acid receptors, retinoid X receptors, peroxisome proliferator‐activated receptors, lipid X receptors, and farnesoid X receptors increase myelin phagocytosis by murine bone marrow–derived macrophages and Raw264.7 cells.
Siyu Wu   +2 more
wiley   +1 more source

Circulating and Tumor-Infiltrating NK Cells From Clear Cell Renal Cell Carcinoma Patients Exhibit a Predominantly Inhibitory Phenotype Characterized by Overexpression of CD85j, CD45, CD48 and PD-1

open access: yesFrontiers in Immunology, 2021
Although natural killer (NK) cells infiltrate clear cell renal cell carcinomas (ccRCC), the most frequent malignancy of the kidney, tumor progression suggests that they become dysfunctional.
Andrea Ziblat   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy