A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig +7 more
wiley +1 more source
Interaction of the mitochondrial calcium/proton exchanger TMBIM5 with MICU1. [PDF]
Zhang L +9 more
europepmc +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Impact of conduit-filling interactions on the efficacy of fiber and hydrogel fillers in nerve conduits. [PDF]
Millesi F +12 more
europepmc +1 more source
ABSTRACT The sociotechnical complexities and hidden dynamics shaping the evolution of digital transformation (DT) and innovation initiatives frequently elude traditional research approaches reliant on retrospective analysis, static and detached observation.
Siobhán Diglas, Kisito F. Nzembayie
wiley +1 more source
Top Managerial Network Relations for Knowledge Transfer: Exploring Gender Differences
ABSTRACT In the ongoing debate surrounding the gender gap in top managerial positions, various possible causes have been explored, with different networking patterns being one of them. However, we still lack detailed insights on how knowledge transfer via networks varies based on gender.
Sonja Sperber, Christian Linder
wiley +1 more source
Interdisciplinary Approach in Pediatric Patients With Recessive Dystrophic Epidermolysis Bullosa: Experience From the Dermatology Service and the Palliative Care and Complex Chronic Patient Team at Sant Joan de Déu Hospital (Barcelona, Spain). [PDF]
Martínez-Ripoll JM +2 more
europepmc +1 more source
Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna +10 more
wiley +1 more source
Mitigating Wetting and Scaling in Air Gap Membrane Distillation Crystallization via SiO<sub>2</sub> Seeding. [PDF]
Flatscher S +4 more
europepmc +1 more source

