Results 221 to 230 of about 229,446 (278)

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig   +7 more
wiley   +1 more source

Interaction of the mitochondrial calcium/proton exchanger TMBIM5 with MICU1. [PDF]

open access: yesCommun Biol
Zhang L   +9 more
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

Impact of conduit-filling interactions on the efficacy of fiber and hydrogel fillers in nerve conduits. [PDF]

open access: yesiScience
Millesi F   +12 more
europepmc   +1 more source

Action Design Research for Actionable Knowledge Production: A Metareflexive Methodology for Digital Transformation and Innovation Studies

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT The sociotechnical complexities and hidden dynamics shaping the evolution of digital transformation (DT) and innovation initiatives frequently elude traditional research approaches reliant on retrospective analysis, static and detached observation.
Siobhán Diglas, Kisito F. Nzembayie
wiley   +1 more source

Top Managerial Network Relations for Knowledge Transfer: Exploring Gender Differences

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT In the ongoing debate surrounding the gender gap in top managerial positions, various possible causes have been explored, with different networking patterns being one of them. However, we still lack detailed insights on how knowledge transfer via networks varies based on gender.
Sonja Sperber, Christian Linder
wiley   +1 more source

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

open access: yesClinical &Experimental Allergy, EarlyView.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna   +10 more
wiley   +1 more source

Mitigating Wetting and Scaling in Air Gap Membrane Distillation Crystallization via SiO<sub>2</sub> Seeding. [PDF]

open access: yesMembranes (Basel)
Flatscher S   +4 more
europepmc   +1 more source

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