Results 81 to 90 of about 1,910,897 (329)
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Comparison of Split Infinitives in Pakistani and British English: A Corpus-based Investigation
Corporum, 2018 This article investigates split infinitives in Pakistani English and British English using Kachru‘s (1985) concentric circles framework.
Bisma Butt, Behzad Anwar
doaj
Native and Non-native English Teachers' Perceptions of their Professional Identity: Convergent or Divergent? [PDF]
Iranian Journal of Language Teaching Research, 2016 There is still a preference for native speaker teachers in the language teaching profession, which is supposed to influence the self-perceptions of native and nonnative teachers.
Zia Tajeddin, Aylar Adeh
doaj
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
CHF Enhancement of Advanced 37-Element Fuel Bundles
Science and Technology of Nuclear Installations, 2015 A standard 37-element fuel bundle (37S fuel bundle) has been used in commercial CANDU reactors for over 40 years as a reference fuel bundle. Most CHF of a 37S fuel bundle have occurred at the elements arranged in the inner pitch circle for high flows and
Joo Hwan Park +2 more
doaj +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
The Rise of English and the Space for Modern Languages
CrossingsThis article examines the space for modern languages in Inner Circle English countries including Australia, UK, and USA against the continued rise of English as a global lingua franca.
M. Obaidul Hamid
doaj +1 more source
Generalized disks of contractivity for explicit and implicit Runge-Kutta methods [PDF]
The A-contractivity of Runge-Kutta methods with respect to an inner product norm was investigated thoroughly by Butcher and Burrage (who used the term B-stability).
Dahlquist, G., Jeltsch, R.
core +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source