Results 41 to 50 of about 146,464 (297)
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Differences and commonalities: art for inner transformation and cultural understanding
Espaço Pedagógico, 2017 Art materializes heightened experiences of transformation that depict human commonalities and particularities through imagery, thereby bringing understanding of self and of different worldviews and practices.
Elizabeth G. Leal
doaj +1 more source
Liminality: Change Starts Within
Challenges, 2023 Change Starts Within is the welcome title to the Inner Development Goals (IDGs) toolkit. The tools are resources to support the inner growth of individuals and organizations committed to the Sustainable Development Goals (SDGs).
Vivianna Rodriguez Carreon
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Amenability and Inner Amenability of Transformation Groups
, 2020 It has some ...
Ebadian, Ali, Jabbari, Ali
openaire +2 more sources
Analyzing the Inner Workings of Transformers in Compositional Generalization
Journal of Natural Language ProcessingThe compositional generalization abilities of neural models have been sought after for human-like linguistic competence. The popular method to evaluate such abilities is to assess the models' input-output behavior. However, that does not reveal the internal mechanisms, and the underlying competence of such models in compositional generalization remains
Ryoma Kumon, Hitomi Yanaka
openaire +3 more sources
Reimagining Porto's Inner Beltway: A Regenerative Urban Transformation
ZarchPorto's Via de Cintura Interna (VCI) is an urban motorway that, paradoxically, contributes to the territory's integration and fragmentation. Its urban and environmental impact extends across a vast area along its edges, threatening the city's ...
Marcela Percú, Teresa Calix
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Determination of α-mannan content in composite yeast cultures by enzymatic hydrolysis HPLC-UV method
Frontiers in NutritionBackgroundComposite yeast culture (CYC) serves as an important functional feed additive. The content of its active ingredient, α-mannan, directly affects product quality and efficacy.
Xiaojie Zhang +11 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source