Results 181 to 190 of about 263,338 (353)
Justice at Risk? The Influence of Recidivism Risk Information on Evaluation of Evidence and Determination of Guilt. [PDF]
De Beuf TLF +3 more
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Algorithms on Trial: Does evaluative probabilistic reporting of forensic evidence infringe the presumption of innocence? [PDF]
Sallavaci O.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Understanding Attorneys' Plea Advice: The Role of Defendant Guilt and Trial Penalties. [PDF]
Burke JL, Wilford MM, Yang Y.
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The effects of screen habits on attentional skills and prosocial behaviors in 6-to 36-month-old toddlers. [PDF]
Gillioz E, Gentaz E, Lejeune F.
europepmc +1 more source

