Results 41 to 50 of about 12,531 (316)

The presumption of innocence as a constitutional phenomenon

open access: yesПравоприменение, 2023
Report. The presumption of innocence is a legal phenomenon that constantly attracts the attention of researchers. It is considered in legal science from the point of view of its origin, legal formalization, content and meaning.
A. N. Shupitskaya
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Syphllis of the Innocent [PDF]

open access: yesSouthern Medical Journal, 1915
n ...
openaire   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

The Phoniness in the Novel The Catcher in the Rye By J.D. Salinger

open access: yesLinguistika Kultura, 2023
This research seeks to explain why Holden believes everyone is a liar, why conflicts emerge between novel characters, and how rivalry affects the characters in J.D. Salinger's The Catcher in the Rye.
Salsabila Fajrina Rizal
doaj  

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Nordic Childhoods in Barn

open access: yesBarn
In connection with the 40th anniversary of the journal Barn in 2023, the editorial team hosted an anniversary conference in Trondheim, Norway. After the conference, we invited a small number of participants to contribute to a special issue on the ...
Marit Ursin   +2 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

The slaughter of the innocents [PDF]

open access: yesAmerican Journal of Obstetrics and Gynecology, 1922
n ...
openaire   +3 more sources

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