Results 31 to 40 of about 33,537 (273)

El compromís amb la renovació pedagògica [PDF]

open access: yes, 2016
L’article planteja una reflexió crítica sobre el concepte i la pràctica de la innovació educativa. En primerlloc, s’analitzen els termes innovació i renovació i s’intenta explicar què signifiquen per aprofundir en el sentit il’abast dels canvis en ...
Esteve, M. del Mar
core  

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra   +17 more
wiley   +1 more source

Estalviar en R+D+I surt car [PDF]

open access: yes, 2015
A Catalunya parlar d'innovació s'ha convertit gairebé en un tòpic. Sentim en declaracions i discursos que la R+D+I hauria de salvar l'economia del país, però, realment, quants dels que ho diuen s'ho creuen?
Canela Campos, Enric I.
core  

Semiconducting Pt Structures Stabilized on 2D MoS2 Crystals Enable Ultrafast Hydrogen Evolution

open access: yesAdvanced Materials, EarlyView.
The interaction of small Pt particles with 2D MoS2 crystals can stabilize bilayer Pt structures, with a semiconducting electronic structure. The semiconducting electronic structure of Pt bilayers constitutes the so far unexplored transition domain between the bulk‐like, metallic band structure of compact nanoparticles and the discrete atomic orbitals ...
Tamás Ollár   +13 more
wiley   +1 more source

Innovation and social challenges in Catalonia seminar [PDF]

open access: yes, 2019
Discurs en el Seminari Innovació i reptes socials a Catalunya pronunciat per Josep A. Planell al Palau Macaya, Barcelona.Speech at the Innovation and social challenges in Catalonia seminar pronounced by Josep A.
Planell Estany, Josep A.
core  

Region‐Selective Growth of Cu2O Shell on Gold Nanoprisms

open access: yesAdvanced Materials Interfaces, EarlyView.
Molecular patches created on the surface of gold nanoprisms enable the region‐selective growth of a Cu2O shell on the prisms, ensuring simultaneously the intimate contact between the metal and semiconductor phases and the accessibility of the high‐intensity plasmonic near‐field regions.
Ziyoda Ganieva   +4 more
wiley   +1 more source

The Health Impact Fund: a new paradigm in pharmaceutical innovation [PDF]

open access: yes, 2014
Hem après que la velocitat i la qualitat de la innovació es poden augmentar molt mitjançant la concessió als innovadors de monopolis temporals, com ara patents o drets d'autor, que els permeten obtenir guanys mitjançant el cobrament de marges elevats ...
Pogge, Thomas
core   +1 more source

Innovación Social: Definiciones, Métricas, Temáticas clave, Agentes y Enfoques de impacto

open access: yesRevista Galega de Economía, 2023
Este artículo analiza las tendencias de las investigaciones sobre Innovación social publicadas en la Social Science Citation Index (SSCI) de la Web of Science. Se identifica sus métricas, definiciones, características, agentes y enfoques, realizando una investigación bibliométrica con el software “Bibliometrixâ€, así como una revisión ...
openaire   +1 more source

Capturing the Electrical Activity of all Cortical Neurons: Are Solutions Within Reach?

open access: yesAdvanced Science, EarlyView.
Despite advancements in implantable electrode technology, challenges persist in scaling up these devices to record most of the neuronal activity across the cortex. This review explores the limitations of both rigid and flexible probes, including tissue damage and foreign body response, while also discussing emerging biohybrid strategies.
Attila Kaszás   +5 more
wiley   +1 more source

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