Results 41 to 50 of about 139 (139)
Effect of COMT and UGT1A Variants on Clinical Response to Opicapone in Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. Symptomatic treatment is based on dopaminergic replacement. With disease progression, the initial benefit of levodopa becomes inconsistent, and motor complications emerge.
Elena Ojeda‐Lepe +15 more
wiley +1 more source
R&D Organization and Corporate Social Responsibility Specialization
Managerial and Decision Economics, EarlyView.ABSTRACT In this paper, we examine whether the scope of corporate social responsibility (CSR) should be broad or narrow. A broad scope covers both production and R&D investment decisions, while a narrow scope applies only to production decisions. We show that both firms' choices and the government's preferences depend on the level of CSR concern and on
Quan Dong +2 more
wiley +1 more source
Apathy in Lewy Body Disorders: A Position Paper
Movement Disorders, EarlyView.Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky +12 more
wiley +1 more source
Phytotherapy Research, EarlyView.Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo +3 more
wiley +1 more source
Sustainable Development, EarlyView.ABSTRACT This study examines the role of social capital in designing and implementing more effective governance strategies to improve the state of the Tagus River's significantly deteriorated middle reach (Spain). We employed social network analysis (SNA) to evaluate the bonding, bridging and linking social capital and the quality of stakeholder ...
Leticia Blázquez +2 more
wiley +1 more source
Social Sustainability in Circular Bioeconomy Business Models: Insights From Argentina
Sustainable Development, EarlyView.ABSTRACT Research on circular bioeconomy business models (CBEBM) has largely prioritised environmental and economic aspects, leaving out the social pillar. To address this gap, this paper analyses to what extent and in what ways social sustainability is integrated into CBEBM, based on 12 cases from northern Argentina, a region with high potential for ...
Celina N. Amato +2 more
wiley +1 more source
The Circular Economy in European Union Supply Chains: A Literature Review
Sustainable Development, EarlyView.ABSTRACT This research aims to analyze the implementation of the circular economy (CE) in European Union (EU) supply chains (SC), highlighting its potential to transform production systems and maximize resource efficiency while minimizing waste. Our study identifies the major trends and advancements in this field, focusing on the barriers that prevent ...
Luis Oswaldo Rodríguez‐Mañay +2 more
wiley +1 more source
Sustainable Development, EarlyView.ABSTRACT This study examines how home‐ and host‐country institutions jointly shape the impact of foreign direct investment (FDI) on firms' climate action commitments (CAC) in emerging markets. Drawing on New Institutional Economics and Varieties of Capitalism, we conceptualize FDI as a mechanism of institutional transmission through which multinational
Jose Pla‐Barber, David Tobón‐Orozco
wiley +1 more source