Results 191 to 200 of about 6,801,825 (368)

Innovation

Journal of the American College of Cardiology, 2013
openaire   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Mercantilist and protectionist shocks on innovation, growth, and economic policy in European regions. [PDF]

J Evol Econ
McCann P, Ortega-Argilés R, Thissen M, Hsu MW.   +3 more
europepmc   +1 more source

Exploratory Innovation, Exploitative Innovation and Peformance: Effects of Organizational Antecedents and Environmental Moderators

Management Sciences, 2006
Justin J. P. Jansen, F. V. D. Bosch, H. Volberda   +2 more
semanticscholar   +1 more source

Follow-On Biologics Legislation: Striking a Balance Between Innovation and Affordability

, 2010
Brian B. Bouggy
openalex   +2 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Innovation Agile : Regards Pluridisciplinaires

Technologie et Innovation, 2019
Laurent Dupont, Laure Morel
doaj   +1 more source

Creating A Multi-Criteria Decision Analysis Tool to Enhance Value-Based Purchasing of Generic and Biosimilar Medications in Saudi Arabia: A Pilot Study. [PDF]

Clinicoecon Outcomes Res
Alruthia Y, Alhajri H, Almohammed OA, Balkhi B, Alsaqa'aby MF, Almuqbil MA, Al-Abdulkarim HA, Almutairi AR.   +7 more
europepmc   +1 more source

Digital Innovation Management: Reinventing Innovation Management Research in a Digital World

MIS Q., 2017
S. Nambisan, K. Lyytinen, A. Majchrzak, Michael Song   +3 more
semanticscholar   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source