Results 151 to 160 of about 557,025 (268)

From the gene to the clinic: Key milestones in the PI3Kδ journey. [PDF]

J Immunol
Vanhaesebroeck B.
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Exploring perceived awareness, barriers and enablers of pregnant women towards physical activity in Ethiopian cities: a qualitative study. [PDF]

BMC Pregnancy Childbirth
Endalew ES, Tucho GT, Mattisson K, Oudin A, Papadopoulou E, Girmay AM, Denu ZA, Garedew MG, Kedir I, Moges T, Tessema M, Malmqvist E.   +11 more
europepmc   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Cu-MOFs Nanozymes with Ascorbate Oxidase and Peroxidase-like Activity for Sensitive Fluorometric Detection of Total Antioxidant Capacity in Fruits. [PDF]

Nanomaterials (Basel)
Huang Y, Chen J, Nasi A, Zhao Y, Ding X, Xu D, Lyu F, Xu D, Zhang M, Chen G, Liu G.   +10 more
europepmc   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Exploring the antimalarial potential of (+)-2,2'-epicytoskyrin A: in vitro and in vivo studies of a bioactive metabolite from endophytic fungus Diaporthe sp. GNBP-10. [PDF]

Malar J
Novita R, Fathoni A, Waluyo D, Suprayogi A, Darusman HS, Nugraha AB, Nurkanto A, Ilmi H, Nozaki T, Agusta A.   +9 more
europepmc   +1 more source

ANALYSIS OF INNOVATION ACTIVITIES

The article analyzes the dynamics of innovation activity development in the Republic of Uzbekistan, as well asin the Namangan region. Statistical data for 2015–2024 are used to assess quantitative indicators of innovation activity(implemented innovations, expenditures on innovation and R&D, the number of performing organizations, and the shareof ...
openaire   +1 more source

RESOURCES OF INNOVATIVE ACTIVITY

Russian Journal of Economics and Law, 2009
The article views the aspects of innovation process management. The author analyzes the growth dynamics of innovative-active enterprises by types of innovations, as well as the innovational potential of the Russian Federal Districts.
openaire   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source