Results 111 to 120 of about 923,769 (294)

INNOVATION PERFORMANCE IN EUROPEAN UNION [PDF]

The enlargement of the European Union calls for specific action to be taken. People in the candidate countries have often had to display a capacity for entrepreneurship in adapting to the transformation of their economies.
Irina Gabriela Radulescu
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Product and process innovation and the decision to export : firm-level evidence for Belgium [PDF]

Using data from the Community Innovation Survey for Belgium in two consecutive periods, this paper explores the relationship between firm-level innovation activities and the propensity to start exporting.
VAN BEVEREN, Ilke, VANDENBUSSCHE, Hylke
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Elderly Golden Age School (EGAS): a strategy to promote health and prosperity elderly in Indonesia

Humanities & Social Sciences Communications
Most elderly citizens face health problems and difficulties although they are economically productive and independent. This study developed a prototype for promoting health and prosperity within the Elderly Golden Age School (EGAS) for ageing populations.
Iswari Hariastuti, Muhammad Dawam, Sri Sugiharti, Tri Suratmi, Dwi Endah Kurniasih, Dwi Budiningsari, Wahyu Utomo, Muthmainnah Muthmainnah, Yuli Puspita Devi   +8 more
doaj   +1 more source

Environmental innovation: Using qualitative models to identify indicators for policy [PDF]

Environmental innovation is an essential part of a knowledge based economy, as environmental innovation makes economies more efficient by encouraging and facilitating the use of fewer material or energy inputs per unit of output.
Arundel, Anthony, Kanerva, Minna, Kemp, Rene   +2 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Adapting innovation systems indicators to assess eco-innovation [PDF]

A large amount of work has analysed systems approaches to innovation and investigated associated methods of innovation measurement. However, relatively little of this literature has discussed the measurement of eco-innovation. Policies and measures to promote eco-innovation are hampered by a lack of relevant data and indicators.
Spiers, J., Pearson, Peter J. G., Foxon, T.   +2 more
openaire  

Measuring agricultural innovation system properties and performance: Illustrations from Ethiopia and Vietnam [PDF]

"The rapidly changing nature of the global food and agriculture system suggests the need to rethink how innovation can contribute to developing-country agriculture.
Kelemework, Dawit, Spielman, David J.
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source