What can healthcare systems learn from looking at tensions in innovation processes? A systematic literature review. [PDF]
BMC Health Serv Res, 2022 Haring M +3 more
europepmc +1 more source
What does an inventory of recent innovation experiences tell us about agricultural innovation in Africa? [PDF]
, 2012 Within the context of the FP7 JOLISAA project (JOint Learning in and about Innovation Systems in African Agriculture), an inventory of agricultural innovation experiences was developed in three African countries: Kenya, South Africa and Benin.
Floquet, Anne +6 more
core
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Interaction management in rural innovation processes
Ciencia y Tecnología Agropecuaria, 2018 Product innovation, production and marketing, results from the interaction among several actors. Thus, the hub extension model of the governmental program MasAgro seeks to be a space in which farmers, extension workers, input suppliers, government ...
Elizabeth Roldán Suárez +3 more
doaj +1 more source
Addressing responsibility in innovation processes for sustainability: Lessons for responsible management of sustainable innovation form a systematic literature review. [PDF]
Front Res Metr Anal, 2022 Mangelkramer D.
europepmc +1 more source
Factors affecting multifunctional teams in innovation processes [PDF]
Structuring the innovation process and managing multifunctional teams is a basic prerequisite successful innovation. A well-structured process gives the possibility to implement effective multifunctional teamwork.
Shen, Xin
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The role of foreign technologies and R&D in innovation processes within catching-up CEE countries. [PDF]
PLoS One, 2021 Prokop V +3 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source