Results 151 to 160 of about 2,064,971 (305)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Toward behavioural innovation economics – Heuristics and biases in choice under novelty [PDF]
A framework for ‘behavioural innovation economics’ is proposed here as a synthesis of behavioural economics and innovation economics in the specific context of choice under novelty.
Jason Potts, Kate Morrison
core
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Learning while (re)configuring: Business model innovation processes in established firms. [PDF]
Strateg Organ, 2016 Berends H +3 more
europepmc +1 more source
HOW TO INNOVATE? PRODUCT INNOVATION VS PROCESS INNOVATION
, 2019 There are many studies on innovation. Some of the studies suggest that innovation is a process, while others suggest that process innovation is an alternative and supportive for product innovation. Some of these studies suggest that it is possible to succeed by focusing more on one approach than on the other, while some studies suggest that ...
openaire +2 more sources
Incorporating a new technology into agent-artifact space. The case of control systems automation. [PDF]
We contribute to the debate on innovation theory and policy by exploring, through the interpretative framework provided by Lane and Maxfield’s theory of innovation (1997; 2005), a set of case studies concerning the implementation of a new technology for ...
Federica Rossi +3 more
core
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
The Role of Regional Innovation Systems in a Globalizing Economy: Comparing Knowledge Bases and Institutional Frameworks in Nordic Clusters [PDF]
In order to advance the understanding of which types of regional innovation system represent effective innovation support for what kinds of industry in different regions analyses must be contextualized by reference to the actual knowledge base of various
Asheim, Bjørn, Coenen, Lars
core
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Organizational Competencies and Innovation Performances: The Case of Large Firms in Belgium [PDF]
The objective of this paper is to assess whether large firms' organizational competencies affect their innovation performances. About 40 organizational sub-competencies are defined and measured through an original survey questionnaire answered by 148 ...
Peeters, Carine +1 more
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