Results 151 to 160 of about 1,855,001 (308)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
A better model for care—virtual care coordination
International Journal of Integrated Care, 2012 Chris Herbert, Claire Medd
doaj +3 more sources
Innovation strategies in the presence of technology markets: evidence from Spanish innovative firms [PDF]
The development of markets for technology has eased the acquisition of technology and reshaped the innovation strategies of firms that we classify as producers of innovations or as imitators.
Arbussà, Anna, Coenders, Germà
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
How clean is clean? Incremental versus radical technological change in coal-fired power plants [PDF]
In the discussion on innovations for sustainable development, radical innovations are frequently called for in order that the transformation of society to a system perceived as sustainable can succeed.
Markewitz, Peter +2 more
core
The institutional dynamics of inequality for women inventors who break with conventional thinking. [PDF]
Proc Natl Acad Sci U S ASowrirajan T, Whalen R, Uzzi B.
europepmc +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Realizing Innovations in Service Firms: new organizational forms and supporting processes [PDF]
This paper describes a number of innovation forms that are of special relevance to firms in the service industry. Not only technological innovations but also organizational innovations have been distinguished.
Aa, W. van der, Elfring, T.
core +1 more source
Postgraduate medical education in fragile conflict-affected settings: A scoping review. [PDF]
PLOS Glob Public HealthAlomar AA +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source