Results 41 to 50 of about 369 (150)

Der Innovationsfonds schafft Impferkenntnisse

Monitor Versorgungsforschung, 2023
Während in den ersten beiden Veranstaltungen der MVF-Fachkongressreihe „Impfstatus“ im Jahr 2021 und 2022 eher die ärztliche Sicht im Mittelpunkt stand, wurde der thematischen Zyklus in diesem Jahr um die der Wissen- sowie der Apothekerschaft erweitert.
openaire   +1 more source

Projekttransfer auf Basis systematischer Übersichtsarbeiten – Konzept zur Weiterentwicklung des Innovationsfonds

Monitor Versorgungsforschung, 2022
Die Empfehlungen des Innovationsausschusses beim G-BA zur Überführung von Innovationsfondsprojekten in die Regelversorgung offenbaren zunehmend ein grundlegendes Problem des bestehenden Transferregimes: Schwierigkeiten bei der Evaluation und die teilweise sehr spezifische Projektgestaltung schränken die Generalisierbarkeit von Projektergebnissen ein ...
Dr. rer. med. Florian Brandt MSc, Jonas Grininger, Christopher Venus, Dr. med. Dr. med. dent. Christoph Homann MBA, Tim Hollmann   +4 more
openaire   +2 more sources

Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN‐TU‐001 trial

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION Monoclonal anti‐amyloid therapies are now accessible, but how these treatments influence changes within the brain is still not clear. We investigated overall and regional change in amyloid removal, glucose metabolism, and atrophy in trial participants with dominantly inherited Alzheimer's disease (DIAD). METHODS In the DIAN‐TU‐001
Austin McCullough, Charles D. Chen, Brian A. Gordon, Nelly Joseph‐Mathurin, Clifford R. Jack Jr, Robert Koeppe, Russ Hornbeck, Deborah Koudelis, Nicole S. McKay, Diana A. Hobbs, Shaney Flores, Sarah J. Keefe, Neelum T. Aggarwal, Ricardo F. Allegri, Sarah B. Berman, Thomas Bird, Sandra E. Black, William S. Brooks, Jasmeer P. Chhatwal, Gregory S. Day, Martin R. Farlow, Nick C. Fox, Serge Gauthier, Lawrence S. Honig, Ging‐Yuek Hsiung, Mathias Jucker, Johannes Levin, Mario Masellis, Colin Masters, Patricio Chrem Mendez, John M. Ringman, B. Joy Snider, Stephen Salloway, Peter R. Schofield, Hiroyuki Shimada, Kazushi Suzuki, Christopher H. van Dyck, Gregory Klein, David B. Clifford, Carlos Cruchaga, Jason Hassenstab, Yan Li, Eric McDade, Susan Mills, John C. Morris, Richard J. Perrin, Charlene Supnet‐Bell, Guoqiao Wang, Chengjie Xiong, Randall J. Bateman, Tammie L. S. Benzinger, for the DIAN‐TU Study Team   +51 more
wiley   +1 more source

Alzheimer's disease and its co‐pathologies: Implications for hippocampal degeneration, cognitive decline, and the role of APOE ε4

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION In neurodegenerative dementias, the co‐occurrence and interaction of amyloid β peptide (Aβ), tau pathology, and other pathological lesions confound their individual contributions to neurodegeneration and their modulation by risk factors.
Klara Gawor, Sam Verrept, Geethika Arekatla, David Wouters, Alicja Ronisz, Moritz Hecht, Celeste Laureyssen, Helena Ver Donck, Bas Lahaije, Simona Ospitalieri, Mathieu Vandenbulcke, Markus Otto, Christine A. F. von Arnim, Estifanos Ghebremedhin, Bernard Hanseeuw, Rik Vandenberghe, Matthew Blaschko, Alejandro Sifrim, Kristel Sleegers, Dietmar Rudolf Thal, Sandra O. Tomé   +20 more
wiley   +1 more source

Safety considerations of semaglutide in the potential treatment of Alzheimer's disease: A pooled analysis of semaglutide in adults aged ≥ 65 years

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 2, April-June 2025.
Abstract INTRODUCTION The evoke/evoke+ trials are investigating semaglutide in a population with early Alzheimer's disease (AD). Specific analyses of semaglutide safety data in older adults are limited; therefore, in the current analysis, we aimed to evaluate safety considerations with semaglutide in adults ≥ 65 years.
Marwan Sabbagh, Cristina Boschini, Sharon Cohen, Magnus Fugger, Frank Jessen, Sune Dandanell, Sue D. Pedersen, Luis Rafael Solís Tarazona, Vanita R. Aroda   +8 more
wiley   +1 more source

Tree diversity shapes the spectral signature of light transmittance in developing forests

Ecology, Volume 106, Issue 3, March 2025.
Abstract Greater tree diversity often increases forest productivity by increasing the fraction of light captured and the effectiveness of light use at the community scale. However, light may shape forest function not only as a source of energy or a cause of stress but also as a context cue: Plant photoreceptors can detect specific wavelengths of light,
Laura J. Williams, Kyle R. Kovach, J. Antonio Guzmán Q., Artur Stefanski, Raimundo Bermudez, Ethan E. Butler, Domitille Coq‐‐Etchegaray, Catherine Glenn‐Stone, Peter Hajek, Johanna Klama, Belinda E. Medlyn, Christian Messier, Aboubakr Moradi, Alain Paquette, Maria H. Park, Michael Scherer‐Lorenzen, Philip A. Townsend, Peter B. Reich, Jeannine Cavender‐Bares, Meredith C. Schuman   +19 more
wiley   +1 more source

The History of a Quiet-Sun Magnetic Element Revealed By ImaX/Sunrise

, 2014
Isolated flux tubes are considered to be fundamental magnetic building blocks of the solar photosphere. Their formation is usually attributed to the concentration of magnetic field to kG strengths by the convective collapse mechanism.
Toro, José Carlos del, Solanki, S., Bellot Rubio, L., Schmidt, W., Bonet, J., Martinez Pillet, V., Bellot Rubio, Luis R., Solanki, S. K., Requerey, Iker S., Requerey, I., Martínez Pillet, Valentín, Del Toro Iniesta, J., Bonet, José A.   +12 more
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Low‐Frequency Deep Brain Stimulation in Non‐Rapid Eye Movement Sleep Modifies Memory Retention in Parkinson's Disease

Movement Disorders, Volume 40, Issue 2, Page 285-291, February 2025.
Abstract Background and Objective Memory impairment is a frequent and debilitating symptom in neurodegenerative disorders. The objective of this study was to provide proof‐of‐principle that deep brain stimulation during sleep can modify memory consolidation in people with Parkinson's disease depending on the stimulation frequency that is applied ...
Damian M. Herz, Jenny Blech, Yaroslav Winter, Gabriel Gonzalez‐Escamilla, Sergiu Groppa   +4 more
wiley   +1 more source

Dynamics of Multi-Cored Magnetic Structures in the Quiet Sun

, 2015
We report on the dynamical interaction of quiet-Sun magnetic fields and granular convection in the solar photosphere as seen by Sunrise. We use high spatial resolution (0farcs15–0farcs18) and temporal cadence (33 s) spectropolarimetric Imaging ...
Martinez Pillet, V., Toro, José Carlos del, Bellot Rubio, Luis R., Solanki, S., Requerey, Iker S., Requerey, I., Martínez Pillet, Valentín, Del Toro Iniesta, J., Solanki, Sami K., Bellot Rubio, L., Schmidt, W., Schmidt, Wolfgang   +11 more
core   +1 more source

European guidelines for the diagnosis and treatment of pancreatic exocrine insufficiency: UEG, EPC, EDS, ESPEN, ESPGHAN, ESDO, and ESPCG evidence‐based recommendations

United European Gastroenterology Journal, Volume 13, Issue 1, Page 125-172, February 2025.
Abstract Pancreatic exocrine insufficiency (PEI) is defined as a reduction in pancreatic exocrine secretion below the level that allows the normal digestion of nutrients. Pancreatic disease and surgery are the main causes of PEI. However, other conditions and upper gastrointestinal surgery can also affect the digestive function of the pancreas. PEI can
J. Enrique Dominguez‐Muñoz, Miroslav Vujasinovic, Daniel de la Iglesia, Djuna Cahen, Gabriele Capurso, Natalya Gubergrits, Peter Hegyi, Pali Hungin, Johann Ockenga, Salvatore Paiella, Lukas Perkhofer, Vinciane Rebours, Jonas Rosendahl, Roberto Salvia, Isabelle Scheers, Andrea Szentesi, Stefanos Bonovas, Daniele Piovani, J. Matthias Löhr, on behalf of the European PEI Multidisciplinary Group, Hana Algül, Livia Archibugi, Marianna Arvanitakis, Sorin Barbu, Georg Beyer, Mihailo Bezmarevic, Frank Bodewes, Marja A. Boermeester, Dmitry Bordin, Marco Bruno, Güralp Ceyhan, Laszlo Czako, Ferdinando D'Amico, Enrique De Madaria, Julian De Martino, Pierre H. Deprez, Christos Dervenis, Petr Dité, Asbjørn Drewes, Sinead N. Duggan, Deniz Duman, Trond Engjom, Nils Ewald, Ovidiu Fabian, Pierluigi Fracasso, Helmut Friess, Jens Brøndum Frøkjær, Luca Frulloni, Sebastien Gaujoux, Cristian Gheorghe, Sophie Gohy, Philip Hardt, Truls Hauge, Andrew Hopper, Julio Iglesias‐Garcia, Jutta Keller, Mariia Kiriukova, Jörg Kleeff, Alexander Kleger, Andrea Laghi, José Larino‐Noia, Johanna Laukkarinen, John Leeds, Björn Lindkvist, Etna Masip, Giovanni Marchegiani, Amir Mari, Emma Martinez‐Moneo, Julia Mayerle, Anders Molven, Alexey Okhlobystin, Nikola Panic, Andrea Parniczky, Raffaele Pezzilli, Mary Phillips, Goran Poropat, Jelena Rakic Matic, Keith Roberts, Stuart Robinson, Vasile Sandru, Alain Sauvanet, Alexander Schneider, Oleg Shvets, Serena Stigliano, Davor Stimac, Oliver Strobel, Hester Timmerhuis, Mihaela Udrescu, Szilard Vancsa, Vicki Veness, Michael Wilschanski, Heiko Witt   +91 more
wiley   +1 more source