Results 31 to 40 of about 365 (145)

Hybrid Nanoparticles Separated by Buoyant Density in a Large‐Scale Centrifugal Process

Journal of Polymer Science, Volume 63, Issue 21, Page 4488-4502, 1 November 2025.
Zonal rotors, shaped like hollow bowls, can sort mixtures of macromolecules and polymer nanoparticles based only on their densities, regardless of their actual sizes or shapes. Using these rotors can make a big difference because they do not need to use centrifuge tubes.
Claudia Simone Plüisch, Rouven Stuckert, Alexander Wittemann   +2 more
wiley   +1 more source

Effekte der ischämischen Fern-Präkonditionierung bei jodhaltiger Röntgenkontrastmittelexposition und präexistenter Nephropathie [PDF]

, 2020
Die Applikation von jodhaltigen Röntgenkontrastmitteln wird bei vorbestehender Niereninsuffizienz als Risikofaktor für ein konsekutives akutes Nierenversagen angesehen (Kontrastmittel-assoziierte Nephropathie).
Zielke, Christopher
core   +1 more source

Resolving the effects of functional traits on tree growth rates: The influence of temporal dynamics and divergent strategies by leaf habit

Journal of Ecology, Volume 113, Issue 11, Page 3191-3209, November 2025.
Functional traits are not consistently associated with tree growth rates but instead reflect dynamic resource acquisition and investment strategies over time and between deciduous and evergreen species. Despite this variability, our findings confirm the utility of functional traits to predict tree growth rates, especially when trait effects are ...
Mégane Déziel, Daniel Schoenig, Rita Sousa‐Silva, Eric B. Searle, William C. Parker, Jeannine Cavender‐Bares, Simone Mereu, Michael Scherer‐Lorenzen, Charles A. Nock, Christian Messier, Peter Reich, Artur Stefanski, Ning Dong, Peter Hajek, Dominique Gravel, Alain Paquette   +15 more
wiley   +1 more source

Cost‐Effectiveness of Family Conferences to Reduce Polypharmacy in Frail Older Adults

Journal of the American Geriatrics Society, Volume 73, Issue 10, Page 3009-3020, October 2025.
ABSTRACT Background Cost‐effectiveness of family conferences on deprescribing with joint prioritization of treatment goals in primary care has not been investigated so far. We assessed cost‐effectiveness in the cluster‐randomized controlled COFRAIL trial conducted with general practitioners and 521 older frail patients with polypharmacy cared for at ...
Joseph Montalbo, Charalabos‐Markos Dintsios, Jens Abraham, Eva Drewelow, Manuela Ritzke, Achim Mortsiefer, Birgitt Wiese, Petra Thürmann, Stefan Wilm, Andrea Icks, COFRAIL study group   +10 more
wiley   +1 more source

Two‐year outcomes of epicranial focal cortex stimulation in pharmacoresistant focal epilepsy

Epilepsia, Volume 66, Issue 9, Page 3242-3253, September 2025.
Abstract Objective This study was undertaken to report on the long‐term safety and efficacy of epicranial focal cortex stimulation (FCS) using the EASEE device as adjunctive neuromodulatory therapy in improving seizure control in adults with pharmacoresistant epilepsy originating from one predominant epileptogenic zone.
Andreas Schulze‐Bonhage, Martin Hirsch, Susanne Knake, Ann Mertens, Michael Rademacher, Elisabeth Kaufmann, Josua Kegele, Carolin Jenkner, Volker Coenen, Martin Glaser, Sergiu Groppa, Yaroslav Winter, for the EASEE Study Group   +12 more
wiley   +1 more source

Der Innovationsfonds schafft Impferkenntnisse

Monitor Versorgungsforschung, 2023
Während in den ersten beiden Veranstaltungen der MVF-Fachkongressreihe „Impfstatus“ im Jahr 2021 und 2022 eher die ärztliche Sicht im Mittelpunkt stand, wurde der thematischen Zyklus in diesem Jahr um die der Wissen- sowie der Apothekerschaft erweitert.
openaire   +1 more source

Projekttransfer auf Basis systematischer Übersichtsarbeiten – Konzept zur Weiterentwicklung des Innovationsfonds

Monitor Versorgungsforschung, 2022
Die Empfehlungen des Innovationsausschusses beim G-BA zur Überführung von Innovationsfondsprojekten in die Regelversorgung offenbaren zunehmend ein grundlegendes Problem des bestehenden Transferregimes: Schwierigkeiten bei der Evaluation und die teilweise sehr spezifische Projektgestaltung schränken die Generalisierbarkeit von Projektergebnissen ein ...
Dr. rer. med. Florian Brandt MSc, Jonas Grininger, Christopher Venus, Dr. med. Dr. med. dent. Christoph Homann MBA, Tim Hollmann   +4 more
openaire   +2 more sources

Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN‐TU‐001 trial

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION Monoclonal anti‐amyloid therapies are now accessible, but how these treatments influence changes within the brain is still not clear. We investigated overall and regional change in amyloid removal, glucose metabolism, and atrophy in trial participants with dominantly inherited Alzheimer's disease (DIAD). METHODS In the DIAN‐TU‐001
Austin McCullough, Charles D. Chen, Brian A. Gordon, Nelly Joseph‐Mathurin, Clifford R. Jack Jr, Robert Koeppe, Russ Hornbeck, Deborah Koudelis, Nicole S. McKay, Diana A. Hobbs, Shaney Flores, Sarah J. Keefe, Neelum T. Aggarwal, Ricardo F. Allegri, Sarah B. Berman, Thomas Bird, Sandra E. Black, William S. Brooks, Jasmeer P. Chhatwal, Gregory S. Day, Martin R. Farlow, Nick C. Fox, Serge Gauthier, Lawrence S. Honig, Ging‐Yuek Hsiung, Mathias Jucker, Johannes Levin, Mario Masellis, Colin Masters, Patricio Chrem Mendez, John M. Ringman, B. Joy Snider, Stephen Salloway, Peter R. Schofield, Hiroyuki Shimada, Kazushi Suzuki, Christopher H. van Dyck, Gregory Klein, David B. Clifford, Carlos Cruchaga, Jason Hassenstab, Yan Li, Eric McDade, Susan Mills, John C. Morris, Richard J. Perrin, Charlene Supnet‐Bell, Guoqiao Wang, Chengjie Xiong, Randall J. Bateman, Tammie L. S. Benzinger, for the DIAN‐TU Study Team   +51 more
wiley   +1 more source

Alzheimer's disease and its co‐pathologies: Implications for hippocampal degeneration, cognitive decline, and the role of APOE ε4

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION In neurodegenerative dementias, the co‐occurrence and interaction of amyloid β peptide (Aβ), tau pathology, and other pathological lesions confound their individual contributions to neurodegeneration and their modulation by risk factors.
Klara Gawor, Sam Verrept, Geethika Arekatla, David Wouters, Alicja Ronisz, Moritz Hecht, Celeste Laureyssen, Helena Ver Donck, Bas Lahaije, Simona Ospitalieri, Mathieu Vandenbulcke, Markus Otto, Christine A. F. von Arnim, Estifanos Ghebremedhin, Bernard Hanseeuw, Rik Vandenberghe, Matthew Blaschko, Alejandro Sifrim, Kristel Sleegers, Dietmar Rudolf Thal, Sandra O. Tomé   +20 more
wiley   +1 more source

Safety considerations of semaglutide in the potential treatment of Alzheimer's disease: A pooled analysis of semaglutide in adults aged ≥ 65 years

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 2, April-June 2025.
Abstract INTRODUCTION The evoke/evoke+ trials are investigating semaglutide in a population with early Alzheimer's disease (AD). Specific analyses of semaglutide safety data in older adults are limited; therefore, in the current analysis, we aimed to evaluate safety considerations with semaglutide in adults ≥ 65 years.
Marwan Sabbagh, Cristina Boschini, Sharon Cohen, Magnus Fugger, Frank Jessen, Sune Dandanell, Sue D. Pedersen, Luis Rafael Solís Tarazona, Vanita R. Aroda   +8 more
wiley   +1 more source