Results 61 to 70 of about 649,795 (267)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Principles of the pedagogical system of master of the realistic painting and graphic arts. artist-painter of battlepieces - N.S. Samokisha

open access: yesОсвітній вимір, 2009
"Principles of the pedagogical system of master of the realistic painting and graphic arts. artist-painter of battlepieces - N.S. Samokisha" is examined question about the features of artistic-pedagogical activity of the known Ukrainian artist of large ...
O.O. Scherbakova
doaj  

The substantiation of distance assessment applicability in the knowledge of Morphology as a component of highly qualified specialist training

open access: yesZaporožskij Medicinskij Žurnal, 2013
The article deals with an implementation experience in innovative assessment methods, while teaching Pathology in I.Ya. Horbachevsky Ternopil State Medical University.
P. R. Selskyj, Ya. Ya. Bodnar
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Innovative Approaches to the Use of Artillery in Wildfire Suppression

open access: yesFire
The increasing frequency and intensity of wildfires in hard-to-reach and hazardous areas represents a significant challenge for traditional firefighting methods. Wildfires pose a growing threat to the environment, property, and human lives. In many cases,
Daniel Korec   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

System analysis and information processing to solve the problem of detecting breakdowns of computer information storage

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. One of the important aspects of maintaining the efficient operation of information systems is the condition of computer equipment. The purpose of the study is to describe a method for effective system analysis of the state of a computer's ...
N. M. Kodatsky   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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