Results 41 to 50 of about 1,835,055 (362)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
KEY COMPETENCE AS A BASIS FOR INNOVATION PROJECTS MANAGEMENT
Сучасний стан наукових досліджень та технологій в промисловості, 2019 By the implementing an enterprise development program, the existing key competence of the organization may undergo significant changes. Also introducing innovations, you can get not only benefits, but additional problems and even risks.
Lyudmyla Chernova
doaj +1 more source
Biosensors in cardiology. T-CARE project: a preliminary study on an innovative wearable telemonitoring system [PDF]
, 2022 Francesca Amati +5 more
openalex +1 more source
An innovative cooperative model for the Master Degree Project of Architecture. Overcoming the traditional system. [PDF]
, 2017 http://dx.doi.org/10.4995/HEAD17.2017.6713Although the Bologna’s process has highlighted the need to develop deep and structural changes in the educational institutions, there is a scarce bibliography on innovation projects in Master Degree Projects ...
Garcia-Moreno, Alberto Enrique +2 more
core +3 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
, 2010 This report outlines the process and findings from an innovative project for students. This work was part of the curriculum and involved students working with West Yorkshire Police as part of the safer Leeds project in designing and making a film for ...
Kenyon, AJ +3 more
core
Innovative competitiveness of russian regions [PDF]
, 2015 The article analyses the competitive challenges of Russian regional economies and proposes ways of selecting competitive priorities. The author assumes that selection of priorities for improving a region’s innovative competitiveness should involve not ...
Golova, I.M.
core +2 more sources
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
MODERNIZATION OF POWER BRANCH TAKING INTO ACCOUNT ECOLOGICAL REQUIREMENTS
Russian Journal of Economics and Law, 2013 The article views the issue of environment pollution due to power branch activity, proposes solutions of power industry modernization taking into account the requirements of ecological safety.
A. R. Baskova
doaj