Results 251 to 260 of about 154,198 (309)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Artificial Intelligence in Nursing Education: A Bibliometric Analysis. [PDF]

Nurs Res Pract
Yu X, Wu W, Ni J, Lin Z.
europepmc   +1 more source

MnI‐Functionalized Covalent Organic Framework as Efficient Electrocatalyst for CO2 Reduction in a Catholyte‐Free Zero‐Gap Electrolyzer

Advanced Functional Materials, EarlyView.
This work demonstrates the successful integration of a phenanthroline‐based 2D COF with MnI catalytic sites into a catholyte‐free membrane‐electrode‐assembly cell for CO2 electroreduction. The crystalline COF actively suppresses Mn⁰–Mn⁰ dimerization, achieving a turnover frequency of 617 h⁻¹ at 2.8 V (full‐cell potential), and enabling stable operation.
Laura Spies, Marcos Eduardo G. Carmo, Gonçalves J. Marrenjo, Stephan Reuther, Patrick Ganswindt, Antonio Otavio T. Patrocinio, Thomas Bein, Osmando F. Lopes, Jenny Schneider   +8 more
wiley   +1 more source

The impact of the national reimbursement drug list negotiation policy on the accessibility and utilization of evolocumab and alirocumab in different levels of hospitals: an interrupted time series analysis. [PDF]

Front Pharmacol
Tang W, Li W, Zhang A, Wu H, Lu W, Fan Y.   +5 more
europepmc   +1 more source

AI and big data driven knowledge mapping of exosome-hydrogel research in orthopedic regeneration and tissue engineering. [PDF]

Front Cell Dev Biol
Li Q, Lou L, Wang S, Zhang M.
europepmc   +1 more source

Assessing decadal changes in human exposure near wildfires in a Mediterranean region. [PDF]

Sci Rep
Torres-Vázquez MÁ, Vaglie MD, Kettridge N, Martellozzo F, Miguez-Macho G, Provenzale A, Royé D, Randelli F, Turco M.   +8 more
europepmc   +1 more source

Reviewer Engagement Trends at a Journal: Cause for Concern. [PDF]

PRiMER
Morley CP, Prunuske J, Phillips JP, Wendling AL, Heidelbaugh JJ, Grammer S.   +5 more
europepmc   +1 more source

Innovation breakthrough in the Alzheimer's disease pharmaceutical industry. [PDF]

NPJ Drug Discov
Cheng H, Kang L, Xu Y, Tanzi RE, Zhang C, Wang C.   +5 more
europepmc   +1 more source