Results 241 to 250 of about 691,076 (306)

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

Inoculation with <i>Azospirillum brasilense</i> Associated with Nitrogen Rates on the Yield and Nutritional Value of Giant Sorghum Silage. [PDF]

Animals (Basel)
Chagas LBDC, de Sousa SV, Silva MAD, Vargas JAC, Santos PMD, Casagrande DR, Mariano DC, Okumura RS, Maciel RP.   +8 more
europepmc   +1 more source

Bio-remediation of humid acids from industrial wastewater using wide rot fungi [PDF]

, 2016
López i Losada, Raül
core  

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Manipulating root-associated microbiomes to boost drought resistance in dryland winter wheat with Streptomyces pactum Act12. [PDF]

BMC Microbiol
Li M, Yang R, Bai Q, Yang Z, Huang T, Qiao Y, Yang B, Chen J, Lin W.   +8 more
europepmc   +1 more source

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Lacticaseibacillus rhamnosus H7 shapes flavor-associated microbial-metabolic networks in low-nitrite sausages: insights from a multi-omics correlation study. [PDF]

NPJ Sci Food
Yue Y, Guo S, Liu H, Zhao N, Jia X, Wang N, Ji C, Dai Y, Zhu B, Lin X.   +9 more
europepmc   +1 more source

Higher-dimensional ordination analysis teases out impacts of <i>Bradyrhizobium</i> bioaugmentation on native soil microbial communities. [PDF]

Microbiol Spectr
Kato H, Itakura M, Sato S, Wagai R, Minamisawa K.   +4 more
europepmc   +1 more source

Enhancing water use efficiency and nutritional quality of maize fodder under deficit irrigation with microbial and potassium amendments. [PDF]

BMC Plant Biol
Nawaz H, Türkay C, Akgün İ, Şenyiğit U.   +3 more
europepmc   +1 more source