Results 201 to 210 of about 13,884,826 (327)

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

Advanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law, Takehiro Suzuki, Tsuyohiko Fujigaya, Keiji Numata   +3 more
wiley   +1 more source

PKPD modeling of the inoculum effect of combined ceftazidime/avibactam and colistin against KPC-3 <i>Klebsiella pneumoniae</i> isolate. [PDF]

Antimicrob Agents Chemother
Aubry R, Buyck JM, Chauzy A, Prouvensier L, Decousser J-W, Nordmann P, Wicha SG, Marchand S, Grégoire N.   +8 more
europepmc   +1 more source

Efficacy of Ceftaroline against Methicillin-Susceptible Staphylococcus aureus Exhibiting the Cefazolin High-Inoculum Effect in a Rat Model of Endocarditis

Antimicrobial Agents and Chemotherapy, 2017
Kavindra V. Singh, T. Tran, E. Nannini, V. Tam, C. Arias, B. Murray   +5 more
semanticscholar   +1 more source

Directed Navigation of Magnetotactic Bacteria via Magnetotaxis in a 3D Vasculature‐On‐A‐Chip

Advanced Materials Technologies, EarlyView.
A perfusable vascular network is developed to investigate MTB at the single‐microorganism level. MTB is demonstrated to successfully align and navigate along the magnetic field inside the microvessels. Abstract Magnetotactic bacteria (MTB), inherently motile and self‐powered, are promising biorobotic candidates for targeted anti‐cancer drug delivery ...
Brianna Bradley, Yuji Nashimoto, Aldo Gonzalez‐Lopez, Takeshi Hori, Hirokazu Kaji, Peter L. Davies, Carlos Escobedo   +6 more
wiley   +1 more source

Microbial Contribution to Soiling and Its Impact on Photovoltaic Module Soiling in Arid Zones of the Atacama Desert

Advanced Sustainable Systems, EarlyView.
Microorganisms colonizing photovoltaic surfaces in the Atacama desert form biofilms that enhance particle adhesion and reduce energy yield. This study identifies UV‐resistant bacteria and carotenoid‐producing strains that interfere with PV performance.
Douglas Olivares, Ricardo Ortíz, Luis Rojas‐Araya, María Teresa Mata, Felipe Galleguillos, Jaime Llanos, Carlos Portillo, Valentina Escobar, Aitor Marzo   +8 more
wiley   +1 more source

Polymorphisms in the type A <i>blaZ</i> gene as determinants of the cefazolin inoculum effect in <i>Staphylococcus aureus</i>. [PDF]

Antimicrob Agents Chemother
Lee S, Park S, Kim JN, Lee SO, Lee JE, Lee SH.   +5 more
europepmc   +1 more source

Mathematical modeling of the 'inoculum effect': six applicable models and the MIC advancement point concept. [PDF]

FEMS Microbiol Lett, 2020
Salas JR, Jaberi-Douraki M, Wen X, Volkova VV.   +3 more
europepmc   +1 more source

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

Advanced Science, EarlyView.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su, Sisheng Zhang, Lidi Liang, Haiyi Bai, Mei Bai, Hanjun He, Yayu Wang, Huan Liu, Xiangxiu Liang, Yu Sun, Hong Wu   +10 more
wiley   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source