Results 31 to 40 of about 13,884,826 (327)
Cefazolin inoculum effect among methicillinsusceptible Staphylococcus aureus isolated from patients with skin infections [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2021 Objective. To evaluate frequency and intensity of cefazolin inoculum effect among methicillin-susceptible staphylococci isolated from patients with skin infections. Materials and Methods.
Vaganova А.N. +7 more
doaj +1 more source
Bistable Bacterial Growth Dynamics in the Presence of Antimicrobial Agents
Antibiotics, 2021 The outcome of an antibiotic treatment on the growth capacity of bacteria is largely dependent on the initial population size (Inoculum Effect). We characterized and built a model of this effect in E. coli cultures using a large variety of antimicrobials,
Nelly Frenkel +4 more
doaj +1 more source
bioRxiv, 2023 Carbapenem-resistant Enterobacterales (CRE) are important pathogens that can develop resistance via multiple molecular mechanisms, including hydrolysis or reduced antibiotic influx.
A. J. Cartagena +9 more
semanticscholar +1 more source
Minimal Surviving Inoculum in Collective Antibiotic Resistance
mBio, 2023 A common strategy used by bacteria to resist antibiotics is enzymatic degradation or modification. This reduces the antibiotic threat in the environment and is therefore potentially a collective mechanism that also enhances the survival of nearby cells ...
Lukas Geyrhofer +5 more
doaj +1 more source
Biomedicines, 2022 The inoculum effect (IE) is a well-known phenomenon with beta-lactams. At the same time, the IE has not been extensively studied with carbapenem/carbapenemase inhibitor combinations.
Maria V. Golikova +7 more
doaj +1 more source
Microbiology Spectrum, 2023 Cefiderocol and aztreonam-avibactam (ATM-AVI) both had activity against carbapenem-resistant Gram-negative bacilli, including those that produce metallo-β-lactamases (MBLs).
Yu-Shan Huang +3 more
doaj +1 more source
Inoculum effect with chloroquine and Plasmodium falciparum [PDF]
Antimicrobial Agents and Chemotherapy, 1987 In the studies reported here, we examined the inoculum effect observed with chloroquine and Plasmodium falciparum. The 50% effective doses observed with both chloroquine-susceptible and -resistant parasites increased five- to sevenfold from their baseline values as the inoculum was increased from 2 X 10(5) to 2 X 10(7) parasitized erythrocytes per ml ...
I Y, Gluzman +2 more
openaire +2 more sources
Mathematical Modeling To Characterize the Inoculum Effect [PDF]
Antimicrobial Agents and Chemotherapy, 2010 ABSTRACT Killing by beta-lactams is well known to be reduced against a dense bacterial population, commonly known as the inoculum effect. However, the underlying mechanism of this phenomenon is not well understood. We proposed a semimechanistic mathematical model to account for the reduced in vitro killing
Pratik, Bhagunde +6 more
openaire +2 more sources
Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population [PDF]
, 2020 Since antibiotic resistance is a major threat to global health, recent observations that the traditional test of minimum inhibitory concentration (MIC) is not informative enough to guide effective antibiotic treatment are alarming.
Debski, Pawel R. +9 more
core +1 more source
Effect of Bacteria Inoculums on Compressive Strength
Journal on Today's Ideas - Tomorrow's Technologies, 2021 The use of bio-concrete is increasing in the present day context and researchers are working on strength and durability characteristics of concrete using bacteria species which have shown calcite precipitation. Three different species of bacteria namely P. Fluorescence, B. Pumilis and B.
Pooja Bandekar +5 more
openaire +2 more sources