Results 1 to 10 of about 25,315 (221)
<em>Bacillus anthracis</em> Edema Factor Substrate Specificity: Evidence for New Modes of Action [PDF]
Toxins, 2012 Since the isolation of <em>Bacillus anthracis</em> exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Roland Seifert +2 more
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The purine metabolite inosine monophosphate accelerates myelopoiesis and acute pancreatitis progression [PDF]
Communications Biology, 2022 Metabolomics analysis reveals that inosine monophosphate, a purine metabolite, promotes myelopoiesis and contributes to severe acute pancreatitis in db/db mice.
Xiao-Min Luo +11 more
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Molecular characterization of adenosine monophosphate deaminase 1 and its regulatory mechanism for inosine monophosphate formation in triploid crucian carp [PDF]
Frontiers in Physiology, 2022 Inosine monophosphate (IMP) is the main flavoring substance in aquatic animal, and adenosine monophosphate deaminase1 (AMPD1) gene is a key gene in IMP formation.
Yonghua Zhou +11 more
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Correlation Analysis between AK1 mRNA Expression and Inosine Monophosphate Deposition in Jingyuan Chickens [PDF]
Animals, 2020 In this study, we examined correlations between the deposition of inosine monophosphate (IMP) and mRNA expression of the adenylate kinase 1 (AK1) gene in Jingyuan chicken.
Juan Zhang +11 more
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Substrate cooperativity shapes competitive inhibitor responses in mycobacterial inosine 5′-monophosphate dehydrogenase [PDF]
Journal of Enzyme Inhibition and Medicinal ChemistryInosine 5′-monophosphate dehydrogenase (IMPDH) is a promising antimicrobial target due to its central role in guanine nucleotide biosynthesis. Accurate and reliable kinetic measurements are essential for evaluating inhibitors.
Zdeněk Knejzlík +5 more
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Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds. [PDF]
PLoS ONE, 2015 Tuberculosis (TB) remains a worldwide problem and the need for new drugs is increasingly more urgent with the emergence of multidrug- and extensively-drug resistant TB.
Magdalena Makowska-Grzyska +13 more
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Frontiers in Marine Science, 2022 Inosine monophosphate (IMP) improves the flesh quality of livestock and poultry, but studies about its effect on fishes are limited. The aim of the present study was to investigate the effect of exogenous IMP on the liver health and flesh quality of ...
Wanjie Cai +15 more
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Foods, 2023 A nontargeted fingerprinting approach combined with the chemometrics method and sensory analysis was used to assess the differences in taste-chemical compositions of chicken breast soup with different ages and their sensory qualities.
Lili Zhang +6 more
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Molecular Genetics and Metabolism Reports, 2020 In de novo purine biosynthesis (DNPS), 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (EC 2.1.2.3)/inosine monophosphate cyclohydrolase (EC 3.5.4.10) (ATIC) catalyzes the last two reactions of the pathway: conversion of 5-aminoimidazole ...
Randall C. Mazzarino +6 more
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Journal of Dairy Science, 2022 : A robust method using HPLC-UV was developed to improve the accuracy and repeatability of a quantitative method to detect 5 nucleotides (cytidine-monophosphate, uridine monophosphate, adenosine monophosphate, guanine monophosphate, and inosine ...
Yuanjia Chen +4 more
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