Results 121 to 130 of about 136,770 (269)

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis, Johanna E. Vriezekolk, Frédérique H. C. Bollen, Dirk E. Schrander, Arnt F. A. Schellekens, Bart J. F. van den Bemt   +5 more
wiley   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

A scoping review of quality prescribing indicators, rules and criteria for primary care

British Journal of Clinical Pharmacology, EarlyView.
Medication‐related problems (MRPs) place a substantial burden on the healthcare system, contributing to hospital admissions and significant healthcare costs. Quality prescribing indicators (QPIs), rules and criteria serve to educate prescribers about high risk MRPs and to monitor prescribing behaviours. This study aims to summarize existing indicators,
James Nind, Anna Mackintosh, Emma Maddock, Alana Delaforce, Gregory Peterson, Elizabeth Manias, Johnson George   +6 more
wiley   +1 more source

Performance of prediction models for delayed union and nonunion after fracture: a systematic review and meta-analysis. [PDF]

BMC Musculoskelet Disord
Yin F, Wang X, Luo G, Deng Z, Chen W, Zhang Y.   +5 more
europepmc   +1 more source

Identification of antibiotic allergies in children using prescribing patterns in the electronic medical record

British Journal of Clinical Pharmacology, EarlyView.
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis, Kailey Tang, Renee Dimond, Alice Lei, Amanda Wilkins, Amanda Gwee   +5 more
wiley   +1 more source

Associations between anxiety, somatic pain and sleep disturbances in major depressive disorder and chronic pain: A cross-sectional study with gender-specific insights. [PDF]

Gen Psychiatr
Zhu C, Cheng J, Chen H, Yan J, Li C, Kong X, Hu J, Gao J, Zhang L, Ju P, Xia Q.   +10 more
europepmc   +1 more source

Trends and Outcomes of Naloxone Use for Iatrogenic Opioid Overdose in Patients on General Wards in a Swiss Hospital: A Ten-Year Retrospective Case Series Analysis. [PDF]

Drug Healthc Patient Saf
Würsten M, Meyer-Massetti C, Leuppi-Taegtmeyer A, Goetschi AN.   +3 more
europepmc   +1 more source

“Evil is Real and Attitude is Everything”: Applying Shattered Assumptions Theory to Worldview Changes Following Wrongful Conviction

Behavioral Sciences &the Law, EarlyView.
ABSTRACT Wrongful convictions continue to occur at high rates. Research has revealed that negative posttraumatic cognitive changes are a risk factor for the development and maintenance of posttraumatic stress disorder, yet little research has examined whether exonerees experience posttraumatic cognitive changes, such as changes to their worldview. Thus,
Kathryn A. Thomas, Madeline R. Stenersen, Lily Hoerner, Chloe Kaminsky   +3 more
wiley   +1 more source

Financial burden of older inpatients with multimorbidity in China: a cross-sectional study. [PDF]

Front Public Health
Xian B, Paek SC, Jin W, Marohabutr T.
europepmc   +1 more source