Results 31 to 40 of about 473,924 (251)

Application Of Input-Output Analysis In The Health Care

open access: yesComparative Economic Research, 2014
Usage of the economic analysis in the study of the performance of health care system does not surprise anyone nowadays. Trends that are drawn over the years fluctuate from the technology assessment of health programs – in terms of efficiency, costs or ...
Maciej Jewczak, Jadwiga Suchecka
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Correlation Analysis Algorithm-Based Multiple-Input Single-Output Wiener Model with Output Noise

open access: yesComplexity, 2019
A novel identification algorithm for the correlation analysis-based multiple-input single-output (MISO) neurofuzzy Wiener model with noise is proposed. Firstly, several sets of Gaussian signals are utilized to realize the decoupling between the dynamic ...
Li Jia, Yangyang Li, Feng Li
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Modelling Analysis of Forestry Input-Output Elasticity in China

open access: yesInternational Journal of Forestry Research, 2016
Based on an extended economic model and space econometrics, this essay analyzed the spatial distributions and interdependent relationships of the production of forestry in China; also the input-output elasticity of forestry production were calculated ...
Guofeng Wang   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Marx and Input-Output Analysis and General Equilibrium Theory

open access: yesWorld Review of Political Economy, 2016
This article shows the following: (1) Marx has given a description of the relationship between industries, which is equivalent to Walras's theoretical version of input-output and to Leontief's empirical (monetary) input-output analysis.
Ezra Davar
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

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