Results 51 to 60 of about 2,584,436 (320)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Determination of the relationship between outputs and inputs in agriculture in the EU member states

open access: yesAgricultural and Resource Economics, 2017
The EU member states have established FADN (The Farm Accountancy Data Network) system to collect and process accounting data from agricultural holdings. The system is based on precisely defined methodology that is unique for all member states.
Aleksandra Figurek, Una Vasković
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Applying Multilevel Models to the Input-Output Analysis

open access: yesمجله اقتصاد و توسعه کشاورزی, 2015
In the present study, an application of multilevel modeling approach to the input- output analysis are presented First, the regional input-output table of all provinces in Iran was extracted based on the Adjusted Flegg Location Quotient Method (AFLQ ...
Fateme Hayatgheibi, M. Ghorbani
doaj  

Impact of HEIs on the Scottish economy: new evidence from an HEI-disaggregated input-output approach [PDF]

open access: yes, 2009
This paper measures the regional demand impacts on output and employment of Scottish Higher Education Institutions (HEIs) based on Input-Output tables for the year 2006.
Hermannsson, K.   +3 more
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Grey enterprise input–output analysis

open access: yesJournal of Computational and Applied Mathematics, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Li, Qiao-Xing, Liu, Si-Feng, Lin, Yi
openaire   +2 more sources

Output frequency response function-based analysis for nonlinear Volterra systems [PDF]

open access: yes, 2007
Analysis of nonlinear systems has been studied extensively. Based on some recently developed results, a new systematic approach to the analysis of nonlinear Volterra systems in the frequency domain is proposed in this paper, which provides a novel ...
Bendat   +29 more
core   +1 more source

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