Results 61 to 70 of about 2,584,436 (320)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Revised stochastic analysis of an input-output model. [PDF]

open access: yes
A main difficulty of regional analysis is the inaccuracy of regional input-output data. A natural framework for investigation is stochastic input-output analysis.
Raa, Thijs ten, Steel, Mark F.J.
core   +3 more sources

Using Input-Output Analysis to Measure Healthy, Sustainable Food Systems

open access: yesFrontiers in Sustainable Food Systems, 2020
Our current food systems are hampering efforts to meet the Sustainable Development Goals. Reshaping our food systems could have enormous co-benefits for our populations and planet.
Sinead M. Boylan   +14 more
doaj   +1 more source

PyIO: Input-Output Analysis with Python [PDF]

open access: yes
This is a User Manual about PyIO, an Input-Output analysis tool using Python. Up to date software is available from the Regional Economics Applications Laboratory (University of Illinois at Urbana-Champaign) homepage. http://www.uiuc.edu/unit/real/
Chokri Dridi   +3 more
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

OUTPUT CHANGE IN U.S. AGRICULTURE: AN INPUT-OUTPUT ANALYSIS [PDF]

open access: yes
This paper analyzes output changes in the U.S. agricultural economy from 1972 to 1977 using a 477-sector input-output framework. The empirical model is based on benchmark input-output data from the U.S.
Holland, David W., Martin, R.P.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

An input-output analysis: linkages vs leakages [PDF]

open access: yes
Resorting to input-output analysis, intersectoral linkages are investigated. For such assessment, the distinction between imported and domestically supplied inputs, which has been disregarded so far in empirical analysis, is crucial.
António Rua, Hugo J. Reis
core  

The impact of higher education institutions (HEIs) on the Scottish economy : new evidence from an HEI-disaggregated input-output approach [PDF]

open access: yes, 2009
This paper measures the regional demand impacts on output and employment of Scottish Higher Education Institutions (HEIs) based on Input-Output tables for the year 2006.
Hermannsson, Kristinn   +3 more
core  

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