Results 61 to 70 of about 17,782,647 (300)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Research on Modeling of a Micro Variable-Pitch Turboprop Engine Based on Rig Test Data

open access: yesEnergies, 2020
Exact component characteristics are required for establishing an accurate component level aeroengine model. When component characteristics is lacking, the dynamic coefficient method based on test data, is suitable for establishing a single-input and ...
Xiaochun Zhao   +2 more
doaj   +1 more source

Effective full time employment for location quotients - a proposal

open access: yes, 2010
Disaggregated input-output tables are increasingly used by developers, economic development practitioners and regional planners at the national, state and sub-state level. Although there are various non-survey techniques employed to produce disaggregated
Christie, Julianne (R10279)
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Input-Output Economics and Material Flows [PDF]

open access: yes
This paper argues that resources constitute the fundamental area of overlap between the interests of input-output economists and industrial ecologists. Three misconceptions about input-output economics obscure this fact: the frequent failure to utilize ...
Faye Duchin
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Obtención, análisis y simulaciones de la Matriz Imput-Ouput de la comuna de Punta Arenas The Input-Ouput Matrix of the Punta Arenas City: Description, analisys and simulation

open access: yesMagallania, 2011
El objetivo de este trabajo es mostrar y analizar la matriz input-output de la Comuna de Punta Arenas elaborada para el año 2003. Así, se explican los argumentos básicos del modelo, la forma en que se construye y las principales características de la ...
SERGIO SOZA- AMIGO, JOSÉ MARIPANI
doaj  

EXPERIENCE OF THE INPUT-OUTPUT MODELS APPLICATION TO THE MOLDOVAN ECONOMY

open access: yesEconomy and Sociology, 2019
The main goal of this article is to present an overview of the input-output models which have been applied to Moldovan economy development study. We examined: static input-output model, dynamic input output model restricted by limited energy resources ...
Elvira NAVAL
doaj   +1 more source

Vertical specialisation indicator based on supply-driven input-output model [PDF]

open access: yes
“Import content of exportsâ€, based on Leontief’s demand-driven input-output model, has been widely used as an indicator to measure a country’s degree of participation in vertical specialisation trade. At a sectoral level, this indicator represents
Meng, Bo, Yamano, Norihiko, Webb, Colin
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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