Results 41 to 50 of about 503,576 (254)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Output Multiplier of Iran\'s Economic Sectors: Input-Output Analysis and Network Theory Approach [PDF]

برنامه‌ریزی و بودجه, 2023
The structure of production networks determines the macroeconomic responses to sectorial shocks. Accordingly, key sectors are instrumental in transmitting supply and demand-side shocks.
Esfandiar Jahangard, Jamal Kakaie, Afsaneh Sherkat, Najmeh Sajedianfard   +3 more
doaj  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Improving the European input–output database for global trade analysis

Journal of Economic Structures, 2020
There are increasing numbers of published articles in the field of input–output analysis and modelling that use the GTAP input–output database; particularly, in relation to the estimation of carbon, energy and water footprints and the analysis of global ...
José M. Rueda-Cantuche, Tamas Revesz, Antonio F. Amores, Agustín Velázquez, Marian Mraz, Emanuele Ferrari, Alfredo J. Mainar-Causapé, Letizia Montinari, Bert Saveyn   +8 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Determination of the relationship between outputs and inputs in agriculture in the EU member states

Agricultural and Resource Economics, 2017
The EU member states have established FADN (The Farm Accountancy Data Network) system to collect and process accounting data from agricultural holdings. The system is based on precisely defined methodology that is unique for all member states.
Aleksandra Figurek, Una Vasković
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Applying Multilevel Models to the Input-Output Analysis

مجله اقتصاد و توسعه کشاورزی, 2015
In the present study, an application of multilevel modeling approach to the input- output analysis are presented First, the regional input-output table of all provinces in Iran was extracted based on the Adjusted Flegg Location Quotient Method (AFLQ ...
Fateme Hayatgheibi, M. Ghorbani
doaj  

Economic Impact of EuroPride 2027: An Input–Output Analysis

European Journal of Social Impact and Circular Economy
EuroPride is a major pan-European LGBTQ+ festival attracting international visitors and media attention. This study estimates the potential economic impact of hosting EuroPride 2027 in a European city using Input–Output (I–O) methodology.
Valerio Brescia, Claudia Tarantola, Massimo Cane   +2 more
doaj   +1 more source