Results 71 to 80 of about 2,586,439 (292)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The emission benefits of European integration

open access: yesEnvironmental Research Letters, 2019
Simulating the implications of Brexit on the UK’s emissions embodied in trade with a multi-region input–output table exposes the benefits of European integration. Under 2014 trade volumes, technologies and energy mixes, a hard Brexit—reverting to a trade
Luís Costa, Vincent Moreau
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Estructuras productivas y desarrollo: el caso de la economía chilena || Productive Structures and Development: The Case of the Chilean Economy

open access: yesRevista de Métodos Cuantitativos para la Economía y la Empresa, 2018
Esta investigación se inicia con las siguientes interrogantes: ¿existe consistencia entre la identificación de desarrollo y la estructura económica que se posee?; ¿existen parecidos entre economías identificadas con distintos niveles de desarrollo?; y ...
Soza-Amigo, Sergio, Aroca, Patricio
doaj  

Recent evolution of wine exports in a turbulence period: a multiregional input-output analysis. [PDF]

open access: yesAgric Food Econ, 2023
Carrasco I   +3 more
europepmc   +1 more source

Technology-intensive industries - Input-output analysis [PDF]

open access: yes, 2010
By the analyses included in this paper I tried to quantify â using the input-output method â the amplitude of upstream and downstream linkages between manufacturing industries, structured by technological groups, for Romania and other six EU member ...
Olteanu, Dan
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Impacto económico de los hoteles: aplicación en la ciudad de Sevilla [PDF]

open access: yesPASOS Revista de Turismo y Patrimonio Cultural, 2010
nowadays there is a growing interest in quantifying the economic impact generated by some productive industries or economic activities on the national, regional or local economy.
Miryam González Limón
doaj  

Regional Economic Growth Disparities in Ukraine: Input-Output Analysis Approach

open access: yesScientific Annals of Economics and Business, 2017
Regional inequalities in economic growth had been observed within many countries and regions. This research emphasizes convergence/divergence technique for Ukrainian regions.
Hryhorkiv Vasyl   +3 more
doaj   +1 more source

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