Results 41 to 50 of about 2,160,968 (306)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Storying syndemics: understanding migrant women’s experiences of diabetes and distress through narratives of self-care

open access: yesBMC Public Health
Background Migrant women face disproportionate rates of co-occurring type 2 diabetes and distress globally. Biomedicine’s individualized care model for people with diabetes conceptualizes distress as an added comorbidity to be managed.
Sumaira Khan   +3 more
doaj   +1 more source

Online Permaculture Resources: An Evaluation of a Selected Sample [PDF]

open access: yes, 2016
As a newly-emerging, sustainable approach to landscape management, permaculture seeks to integrate knowledge from several disciplines into a holistic system with emphasis on ecological and social responsibility.
Luchkina, Claire M.
core   +2 more sources

Evidence-based campaigning

open access: yesArchives of Public Health, 2018
Background When promoting public health measures, such as reducing smoking, there are many different approaches, for example providing information, imposing legal restrictions, taxing products, and changing cultures.
Brian Martin
doaj   +1 more source

A New Design Method for Vanadium Redox Batteries in Renewable Energy Systems [PDF]

open access: yes, 2015
This study investigated the behavior of vanadium redox flow batteries (VRFBs), which are batteries capable of easily switching between charging and discharging modes, making them a suitable option for storing intermittent sources of alternative ...
Gibson, Casey   +1 more
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

The contributions of sound to the semiosis of a young man with a severe intellectual disability

open access: yesJournal of World Languages
This paper focuses on vocalisations in the microlanguage of a man with a severe intellectual disability named Bodhi, who is functionally nonverbal. To make meaning, Bodhi deploys a variety of modes of expression, including non-speech vocalisations. These
Dreyfus Shoshana, Ariztimuño Lilián I.
doaj   +1 more source

Instituting: a Legal Practice

open access: yesHumana.Mente: Journal of Philosophical Studies, 2022
This article explores the concept of institution as the legal performance par excellence. It starts by giving an account of the perspective that Merleau-Ponty opens on the notion of institution and aims to show the connection with the concept of ...
Xenia Chiaramonte
doaj  

What is a scientific experiment?: The impact of a professional development course on teachers’ ability to design an inquiry-based science curriculum [PDF]

open access: yes, 2016
Designing inquiry-based science lessons can be a challenge for secondary school teachers. In this study we evaluated the development of in-service teachers’ lesson plans as they took part in a 10-month professional development course in Peru which ...
Furman, Melina Gabriela   +1 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

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