Results 81 to 90 of about 677,147 (285)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Clinical inquiry and scientific inquiry [PDF]
G R, Norman, V L, Patel, H G, Schmidt
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
This chapter explains the contextual inquiry, during which researchers explore the context and relevant stakeholders, including the prospective users. It’s aim is to get a good grasp of the context in which the eHealth technology will be used. This chapter explains this and provides examples of concrete methods that can be used to conduct a contextual ...
Kip, Hanneke +2 more
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Jaws Within Jaws: A Cosmopolitical Ecology of Alien
This article investigates multi-species relations in a group of science fiction narratives featuring extraterrestrial beings, paying particular attention to the Alien movie series.
Eric Macedo
doaj
After any shipping casualty has occurred (eg., a sinking, collision, grounding, death or personal injury due to accident at sea) it has been the custom for an inquiry to be made into its circumstances to see if steps could be taken to improve safety procedures to avoid the recurrence of a similar casualty and to investigate whether any of the mariners ...
openaire +3 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
„Spielen die jetzt Soziologen?“ Nutzerstudien mit ethnografischen Methoden
Ausgehend von den USA ist der Trend zur Nutzerforschung mit Methoden aus der Ethnografie nun auch in Deutschland angekommen. Den Durchbruch brachte die Studie „Studying Students“ (2007) der University of Rochester, deren Ansatz des „Participatory Design“
Corinna Haas
doaj +1 more source

