Results 81 to 90 of about 218,068 (267)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
„Spielen die jetzt Soziologen?“ Nutzerstudien mit ethnografischen Methoden
027.7, 2013 Ausgehend von den USA ist der Trend zur Nutzerforschung mit Methoden aus der Ethnografie nun auch in Deutschland angekommen. Den Durchbruch brachte die Studie „Studying Students“ (2007) der University of Rochester, deren Ansatz des „Participatory Design“
Corinna Haas
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Digital scenography and the mimetic aporia of Richard Wagner's Ring Cycle
Journal of Aesthetics & Culture, 2015 This article explores the visual friction between the concealment of technology and the need to stage mimetic scenes in Richard Wagner's Der Ring des Nibelungen. The article relies on the critical reception of the Wagnerian Gesamtkunstwerk in musicology,
Jason R. D’Aoust
doaj +1 more source
Clinical inquiry and scientific inquiry [PDF]
Medical Education, 1990 G R, Norman, V L, Patel, H G, Schmidt
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Child Protection and PracticeBackground: How victims and survivors of non-recent institutional child abuse – and the advocacy groups that support them – conceptualise justice has become a central concern for policy makers designing redress schemes.
Alasdair Henry +2 more
doaj +1 more source
A Survey of Geospatial Semantic Web for Cultural Heritage
Heritage, 2019 The amount of digital cultural heritage data produced by cultural heritage institutions is growing rapidly. Digital cultural heritage repositories have therefore become an efficient and effective way to disseminate and exploit digital cultural heritage ...
Ikrom Nishanbaev +2 more
doaj +1 more source