Results 51 to 60 of about 320,487 (342)
Inscriptions, 2021 Those who read the essay may be reminded of A.R. Ammon's poem, “Garbage” which a correspondant recently called to my attention. The overlap is coincidental; at time of writing, I was ignorant of that work. This essay investigates meanings of an old term:
David Ritchie
doaj
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The sea in Sumerian literature [PDF]
, 2020 Surveying the references to the sea in Sumerian literature, this paper discusses the general idea that the sea is underrepresented in Mesopotamian cultures of the third millennium BCE.
Lorenzo Verderame
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
After religion: the commitment and love of This Life
Inscriptions, 2021 Review of Hägglund, Martin (2019), This Life: secular faith and spiritual freedom, Anchor Books: New York.
Torgeir Fjeld
doaj
The "handedness" of language: Directional symmetry breaking of sign usage in words
, 2018 Language, which allows complex ideas to be communicated through symbolic sequences, is a characteristic feature of our species and manifested in a multitude of forms.
Ashraf, Md Izhar, Sinha, Sitabhra
core +2 more sources
Unlocking the Secrets of Ancient Writing. The Parallel Lives of Michael Ventris and Linda Schele and the Decipherment of Mycenaean and Mayan Writing [PDF]
, 2000 Catalogue of an exhibition conducted in conjunction with the Eleventh International Mycenological Colloquium held at the University of Texas at Austin in 2000.
Palaima, Thomas G. +2 more
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
, 2018 Für das hellenistische und kaiserzeitliche Rhodos sind verschiedene Gymnasiarchien bezeugt: ein gymnasiarchos der presbyteroi, einer der neoteroi und ein Phylenamt, das mit Fackelläufen verbunden war.
Kah, Daniel
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source