Results 121 to 130 of about 1,456,494 (246)
Advanced Science, EarlyView.Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun +18 more
wiley +1 more source
Advanced Science, EarlyView.The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang +7 more
wiley +1 more source
Research reports : 60th Annual Pacific Northwest Insect Management Conference
Proceedings of the 60th Annual Pacific Northwest Insect Management Conference, held January 8-9, 2001 at the Imperial Hotel in Portland ...
Pacific Northwest Insect Management Conference
core +1 more source
Advanced Science, EarlyView.In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang +8 more
wiley +1 more source
Research reports : 53rd Annual Northwest Insect Management Conference
Proceedings of the 53rd Annual Pacific Northwest Insect Management Conference, held January 10-11, 1994 at the Imperial Hotel in Portland ...
Pacific Northwest Insect Management Conference
core +1 more source
Research reports : 75th Annual Pacific Northwest Insect Management Conference
Proceedings of the 75th Annual Pacific Northwest Insect Management Conference, held January 11-12, 2016 at the Hilton Hotel in Portland ...
Pacific Northwest Insect Management Conference
core
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
Advanced Science, EarlyView.This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
Research reports : 71st Annual Pacific Northwest Insect Management Conference
Proceedings of the 71st Annual Pacific Northwest Insect Management Conference, held January 9-10, 2012 at the Hilton Hotel in Portland ...
Pacific Northwest Insect Management Conference
core +1 more source
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
Research reports : 74th Annual Pacific Northwest Insect Management Conference
Proceedings of the 74th Annual Pacific Northwest Insect Management Conference, held January 12-13, 2015 at the Hilton Hotel in Portland ...
Pacific Northwest Insect Management Conference
core