Results 41 to 50 of about 2,888 (268)
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
ABSTRACT Background Exposures to human pathogens and toxins in licensed facilities in Canada have been monitored by a federal surveillance system since 2015, yet the affected persons (APs) in these incidents remain uncharacterized. This study comprehensively describes APs, highlighting sector‐specific patterns and trends over time.
Emily F. Tran +4 more
wiley +1 more source
Three‐dimensional digital analysis of musteloid masticatory muscle architecture
Musteloids span an enormous breadth of dietary modes within a single superfamily. In this study, we utilize digital dissection techniques to reconstruct the internal 3D anatomy of muscles within the musteloid feeding apparatus, and explore how dietary specializations might alter the size, orientation, and curvature of fascicles therein.
Cassidy E. Davis +6 more
wiley +1 more source
Bite force estimates and morphological correlations of jaw muscles in parrots
Abstract Parrots (Order: Psittaciformes) are renowned for their high bite force (BF) and morphological correlates thereof, including a highly mobile skull and two unique mandibular adductor muscles—m. pseudomasseter and m. ethmomandibularis, with the former being hypothesized to increase force output.
Ana Carolina L. Faillace +3 more
wiley +1 more source
A Date Palm Worker Dies After Being Stung by Bees [PDF]
A date palm tree worker died after being stung by numerous bees while working in an organic date orchard. The victim and a co-worker were spraying the dates with high-pressure water when the incident occurred.
core +1 more source
Abstract Amphisbaenians (Squamata: Amphisbaenidae) are fossorial reptiles with highly specialized cranial morphology, yet their fossil record is frequently limited by fragmentary preservation. This study provides a detailed osteological redescription of the skulls of Amphisbaena braestrupi and Amphisbaena laurenti from the Pleistocene of Lagoa Santa ...
Carolina L. Paiva +2 more
wiley +1 more source
Abstract The ‘Palaeogene strata’ of the Itaboraí Basin (upper Paleocene‐lower Eocene), Southeastern Brazil, has preserved 29 genera and almost 50 species of metatherians (about 65% of its mammalian diversity). Among them, Eobrasilia coutoi Simpson, 1947 is the most enigmatic due to its quite fragmentary nature.
Leonardo M. Carneiro +10 more
wiley +1 more source
Abstract This study presents the first detailed description of bioerosion traces produced by insects in bones from the Santa Cruz Sequence (early Carnian, Santa Maria Supersequence, Brazil). An array of traces is reported, consisting of notches, a tube, trails of grooves attributed to the ichnotaxon Osteocallis mandibulus and ornamented depressions ...
Lucca S. Cunha +2 more
wiley +1 more source
Field samples from breeder duck farms with egg‐production decline were subjected to viral detection, genome sequencing, and virus isolation. Experimental infection demonstrated that duck orbivirus (DORV) causes a significant and persistent reduction in egg production in breeder ducks.
Bing Li +18 more
wiley +1 more source
FUNDAMENTOS: No Brasil, doenças provocadas por picadas de insetos são frequentes, o que torna extremamente importante a execução de medidas profiláticas de forma adequada, sobretudo, em áreas endêmicas como a Amazônia, que recebe um grande contingente de
Jonas Ribas, Ana Maria Carreño
doaj +1 more source

