Results 171 to 180 of about 10,424,695 (290)
Advanced Science, EarlyView.The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang +7 more
wiley +1 more source
The insect- and plant-associated lifestyles of Pseudomonas protegens CHA0 are preserved following serial passage through insect larvae. [PDF]
PLoS PathogZwyssig M +5 more
europepmc +1 more source
Advanced Science, EarlyView.In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang +8 more
wiley +1 more source
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
Advanced Science, EarlyView.This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
The molecular biology of disease vectors collection: celebrating the tenth workshop on genetics, molecular biology, and control of insect vectors of tropical diseases (the Entomol). [PDF]
Parasit VectorsBrandão-Filho SP +2 more
europepmc +1 more source
Advanced Science, EarlyView.A photoelectrochemical circularly polarized light detector combines a multilayer chiral photonic film with a dynamically regulated BiVO4‐RGO‐MXene transducer. Broadband optical modulation from 360 to 830 nm is converted into stable electrical outputs through low‐noise solid‐liquid interfacial charge transfer, enabling self‐powered CPL discrimination ...
Siqin Zhou +5 more
wiley +1 more source
Transient Expression of Bta78 Gene in Nicotiana benthamiana Enhances Whitefly Feeding Activity. [PDF]
Arch Insect Biochem PhysiolAslam MQ, Mansoor S, Jander G.
europepmc +1 more source
Advanced Science, EarlyView.This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou +4 more
wiley +1 more source
Neurological Responses to Scented Insects via Olfactory Stimulation: A Controlled fMRI Study. [PDF]
InsectsHong HE +8 more
europepmc +1 more source