What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora +12 more
wiley +1 more source
Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture
ABSTRACT The high cost of cultivation media remains one of the barriers to the commercialization of cultivated meat. Current serum‐free media reduce reliance on fetal bovine serum but only achieve modest cost savings. Especially at larger scales (> 20 m3), pharmaceutical‐grade amino acids and recombinant proteins remain major cost drivers.
Jelle C. Hoek +3 more
wiley +1 more source
A two-step management strategy was evaluated for rapid feeding suppression and colony elimination of termites (Reticulitermes speratus) infesting wooden cultural heritage structures (WCHS).
Ik-Gyun Im, Gyu-Seong Han
doaj
BODIPY‐based J‐aggregates: From supramolecular chemistry to NIR bioimaging and phototherapies
BODIPY dyes form ordered J‐aggregates through controlled supramolecular self‐assembly, producing narrow, red‐shifted absorption bands with small Stokes shifts. This review highlights design strategies governing J‐aggregation, structure–property relationships, and applications in sensing, bioimaging, and phototherapy, guiding functional BODIPY‐based ...
Pooja Sharma +2 more
wiley +1 more source
Broad complex Z2 functions as an upstream 20E-responsive regulator of the midgut chitinase gene HaCHT4 in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae). [PDF]
Hu D, Li Y, Xie J, Pan H, Liu X.
europepmc +1 more source
Loss, persistence and reversal of phenotypic traits
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni +4 more
wiley +1 more source
Comparative impact of insect growth regulators on mortality and development of Amrasca biguttula (Hemiptera: Cicadellidae). [PDF]
Attia S, Joseph SV.
europepmc +1 more source
Flight of the dragons: a global review of migration in Odonata
ABSTRACT Insects are the most abundant and ecologically important animal migrants. Yet, we know relatively little about the patterns and processes underlying insect migration. Dragonflies (Anisoptera) and damselflies (Zygoptera) comprise the ancient insect order Odonata, whose ancestors were the first organisms to fly on Earth.
Johanna S.U. Hedlund +3 more
wiley +1 more source
Glycosylation and counter-glycosylation define an apple-insect chemical arms race. [PDF]
Teixeira M, Khatri P.
europepmc +1 more source

