Results 41 to 50 of about 405,275 (266)

Selection of Cutting Inserts in Dry Machining for Reducing Energy Consumption and CO2 Emissions

open access: yesEnergies, 2015
Manufacturing processes are responsible for climate change due to the emissions produced as result of energy consumption. This paper analyzes the influence of the cutting conditions and the characteristics of cutting tools on the energy required in ...
Rosario Domingo   +3 more
doaj   +1 more source

Analisis Kerentanan Website SMP Negeri 3 Semarapura Menggunakan Metode Pengujian Rate Limiting dan OWASP

open access: yesINSERT, 2022
Keamanan  sistem informasi sangat penting karena hal ini berkaitan dengan data pribadi, hak akses, integritas, kerahasiaan dan ketersediaan. Sistem informasi saat ini memiliki peranan yang sangat penting baik dalam membantu tercapainya pembelajaran yang ...
Desi Dwi Cahyani   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Transposons disrupt genomic stability and trigger cancers

open access: yesFrontiers in Cellular and Infection Microbiology
Transposons (TEs) are genetic elements that can change their positions within genome. They cause transcriptional activation or repression by inserting into regulatory elements of related genes or by modulating epigenetic modifications on regulatory ...
Weixia Dong   +7 more
doaj   +1 more source

Health Status Assessment Using Lifestyle Indicators [PDF]

open access: yesITM Web of Conferences
Technological development is undergoing rapid proliferation of rapid advancement in technological developments made possible the ever-continuous collection of structured lifestyle and physiological data.
Krishna E. Mohan   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Pengujian dan Evaluasi Lont-Ar “Prasi Berteknologi Augmented Reality”

open access: yesINSERT, 2022
Paper ini akan akan membahas tentang pengujian dan evaluasi pada aplikasi Lont-AR. Lont-AR merupakan sebuah produk seni modern inovatif yang menggabungkan lontar bergambar (di Bali dikenal dengan nama Prasi) dengan teknologi augmented reality (AR ...
I Putu Andika Subagya Putra   +4 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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