Results 81 to 90 of about 405,275 (266)

Substring Counting with Insertions

Algorithms
Substring counting is a classical algorithmic problem with numerous solutions that achieve linear time complexity. In this paper, we address a variation of the problem where, given three strings p, t, and s, we are interested in the number of occurrences of p in all strings that would result from inserting t into s at every possible position ...
Janez Brank, Tomaz Hocevar
openaire   +4 more sources

Thought Insertion Clarified. [PDF]

Journal of consciousness studies : controversies in science & the humanities, 2015
'Thought insertion' in schizophrenia involves somehow experiencing one's own thoughts as someone else's. Some philosophers try to make sense of this by distinguishing between ownership and agency: one still experiences oneself as the owner of an inserted thought but attributes it to another agency.
Ratcliffe, M, Wilkinson, S
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Effect of novel polyethylene insert configurations on bone-implant micromotion and contact stresses in total ankle replacement prostheses: a finite element analysis

Frontiers in Bioengineering and Biotechnology
PurposeThis study investigates the impact of elastic improvements to the artificial ankle joint insert on prosthesis biomechanics to reduce the risk of prosthesis loosening in TAR patients.MethodsCT data of the right ankle was collected from one elderly ...
Zhi Xu, Xiaonan Gong, Zhengyuan Hu, Ruixiang Bian, Ying Jin, Yuwan Li   +5 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Variable-Orifice-Size Nozzle for 3D Printing

Journal of Manufacturing and Materials Processing
This paper presents the general framework of the problem and the basis for the proposed idea, which lies in the design of a new extrusion nozzle for fused-deposition 3D printing, featuring a variable orifice that enables adaptive extrusion control to ...
Jan Bém, Jiří Suder, Aki Mikkola, Tomáš Kot, Jan Maslowski, Ján Babjak, Milan Mihola   +6 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Feature-Level Fusion for Predictive Drug Inventory Management in Hospitals Using XGBoost

INSERT
Background: Effective drug inventory management in hospitals remains a significant challenge due to fluctuating patient needs and dynamic external factors.
Muhammad Furqan Nazuli, Kridanto Surendro   +1 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Komparasi Metode Evaluation based on Distance from Average Solution (EDAS) dan Additive Ratio ASsessment (ARAS) untuk Rekomendasi Pemilihan E-Wallet

INSERT
Perkembangan teknologi yang sangat cepat menjadi alasan dari banyaknya teknologi finansial yang dapat digunakan. E-wallet merupakan produk fintech yang popular dimana berdasarkan data Bank Indonesia diketahui bahwa ada 38 brand e-wallet yang terdaftar ...
Wahyuni Nainggolan, I Gede Mahendra Darmawiguna, Putu Hendra Suputra   +2 more
doaj   +1 more source