Results 81 to 90 of about 4,057 (206)

Socializing, networking and development: a report from the second ‘Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis’ [PDF]

, 2012
In mid-June, the second Young Microbiologists Symposium took place under the broad title of ‘Microbe signalling, organization and pathogenesis’ on the picturesque campus of University College Cork, Ireland.
Barret, Brackman, Brown, Bush, Cascales, Corrigan, Costerton, Coulthurst, D'Autreaux, Davey, Delalez, Fazli, Gerlach, Hagan, Holland, Hood, Housden, Kleanthous, Kuchma, Kuchma, Kuchma, Lawley, Lebeer, Malone, McCarthy, Merritt, Murdoch, O'Connell Motherway, O'Connell Motherway, O'Toole, Porter, Ramsay, Ramsay, Rigel, Roberts, Ryan, Ryan, Ryan, Ryan, Ryan, Schwarz, Sharma, Shioya, Smith, Thompson, Twomey, Waters, Yang, Youle   +48 more
core   +1 more source

Transcriptomic Analyses Unveil Hydrocarbon Degradation Mechanisms in a Novel Polar Rhodococcus sp. Strain R1B_2T From a High Arctic Intertidal Zone Exposed to Ultra‐Low Sulphur Fuel Oil

Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.
Cold‐adapted Rhodococcus sp. strain R1B_2T from Arctic Tupirvik Beach (Northwest Passage) degrades short‐ to long‐chain hydrocarbons in summer seawater (−1°C to 5°C) via a synergistic activity of key hydrocarbon degradation genes (alkB, CYP153, almA, and ladA), with rhlABCR‐linked rhamnolipid production supporting biodegradation.
Nastasia J. Freyria, Antoine‐Olivier Lirette, Brady R. W. O'Connor, Charles W. Greer, Lyle G. Whyte   +4 more
wiley   +1 more source

Mechanisms governing GPCR anterograde transport

FEBS Letters, Volume 599, Issue 17, Page 2420-2438, September 2025.
G protein‐coupled receptors (GPCRs) determine human physiology by transducing ligand binding into intracellular signaling. The transport of nascent GPCRs from the endoplasmic reticulum to the cell surface is critical for cellular responsiveness. We discuss mechanisms regulating GPCR trafficking through secretory organelles, retention of disease‐related
Kevin Assoumou, Sofia Papadogkonaki, Itziar Muneta‐Arrate, Miriam Stoeber   +3 more
wiley   +1 more source

ALB3 Insertase Mediates Cytochrome b6 Co-translational Import into the Thylakoid Membrane [PDF]

Scientific Reports, 2016
AbstractThe cytochrome b6 f complex occupies an electrochemically central position in the electron-transport chain bridging the photosynthetic reaction center of PS I and PS II. In plants, the subunits of these thylakoid membrane protein complexes are both chloroplast and nuclear encoded.
Jarosław Króliczewski, Małgorzata Piskozub, Rafał Bartoszewski, Bożena Króliczewska   +3 more
openaire   +2 more sources

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

Advanced Functional Materials, Volume 35, Issue 37, September 11, 2025.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen, Pengfei Zhang, Fathima Shana Pattar Kadavan, Zhaoning Xu, Tien Thanh Nguyen, Wenshao Li, Manh Tuong Nguyen, Chung Kim Nguyen, Duy Quang Pham, Thi Giang Tuyet Pham, Andrew Hayles, Markos Negash Alemie, Jitraporn Vongsvivut, Vincent Chan, Stephen Peter Kidd, Yunpeng Zhao, Krasimir Vasilev, Vi Khanh Truong   +17 more
wiley   +1 more source

MTCH2 Deficiency Promotes E2F4/TFRC‐Mediated Ferroptosis and Sensitizes Colorectal Cancer Liver Metastasis to Sorafenib

Advanced Science, Volume 12, Issue 36, September 25, 2025.
This study identifies MTCH2 as a crucial regulator of ferroptosis in colorectal cancer (CRC) progression. High expression of MTCH2 is correlated with poor prognosis in CRC patients. Furthermore, MTCH2 depletion induces ferroptosis to suppress CRC liver metastasis via the E2F4/TFRC axis and sensitizes tumors to sorafenib treatment, supporting MTCH2 as a
Pu Xing, Jiangbo Chen, Hao Hao, Xiaowen Qiao, Xinying Yang, Kai Weng, Jie Chen, Lin Song, Tianqi Liu, Yifan Hou, Tongkun Song, Yumeng Ran, Bo Chen, Hong Yang, Wei Zhao, Zaozao Wang, Jiabo Di, Beihai Jiang, Xiangqian Su   +18 more
wiley   +1 more source

Advances in Small Molecule Inhibitors Targeting the Bacterial Lipoprotein Transport System (Lol) in Gram‐Negative Bacteria

Chemistry – An Asian Journal, Volume 20, Issue 17, September 4, 2025.
The lipoprotein transport system (Lol) is a crucial target for combating multidrug‐resistant gram‐negative bacteria. This review discusses the structural and functional aspects of the LolABCDE complex, recent advances in small‐molecule inhibitors, and challenges, such as permeability and resistance.
Saemee Song, Su Yong Shim
wiley   +1 more source

A conserved cysteine residue of Bacillus subtilis SpoIIIJ is important for endospore development. [PDF]

PLoS ONE, 2014
During sporulation in Bacillus subtilis, the onset of activity of the late forespore-specific sigma factor σG coincides with completion of forespore engulfment by the mother cell.
Luísa Côrte, Filipa Valente, Mónica Serrano, Cláudio M Gomes, Charles P Moran, Adriano O Henriques   +5 more
doaj   +1 more source

OXA1L deficiency causes mitochondrial myopathy via reactive oxygen species regulated nuclear factor kappa B signalling pathway

Clinical and Translational Medicine, Volume 15, Issue 6, June 2025.
OXA1L gene bi‐allelic variants cause mitochondrial myopathy. OXA1L deficiency results in combined mitochondrial respiratory chain defects and OXPHOS impairments. OXA1L deficiency leads to elevated ROS production, which may activate the NF‐κB signalling pathway, disturbing myogenic gene expression and triggering cell apoptosis. Abstract Background OXA1L
Yongkun Zhan, Qian Wang, Ya Wang, Yanjie Fan, Dan Yan, Xianlong Lin, Yaoting Chen, Tingting Hu, Nan Li, Weiqian Dai, Hezhi Fang, Yongguo Yu   +11 more
wiley   +1 more source

Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction [PDF]

Nature Communications, 2015
AbstractCanonical membrane protein biogenesis requires co-translational delivery of ribosome-associated proteins to the Sec translocase and depends on the signal recognition particle (SRP) and its receptor (SR). In contrast, high-throughput delivery of abundant light-harvesting chlorophyll a,b-binding proteins (LHCPs) in chloroplasts to the Alb3 ...
Annemarie Horn, Janosch Hennig, Yasar L. Ahmed, Gunter Stier, Klemens Wild, Michael Sattler, Irmgard Sinning   +6 more
openaire   +5 more sources