Results 111 to 120 of about 1,001,632 (316)

Plug & Test at System Level via Testable TLM Primitives [PDF]

open access: yes, 2008
With the evolution of Electronic System Level (ESL) design methodologies, we are experiencing an extensive use of Transaction-Level Modeling (TLM). TLM is a high-level approach to modeling digital systems where details of the communication among modules ...
Navabi, Z.   +12 more
core   +1 more source

A Crossover between Conventional Cross-Coupling and Carbene Insertion Reaction Pathways in a Pd Catalyzed C(sp2)-H Insertion

open access: yes, 2023
Computational methods (Density Functional Theory) along with experimental tools are used to probe the mechanism and stereocontrol in a Pd(II)-catalyzed enantioselective C–H insertion reaction.
Anubhav, Goswami   +2 more
core   +1 more source

Distribution of the ACE Gene Polymorphisms in Type 2 Diabetes Mellitus Patients, Their Associations with Nephropathy Biomarkers and Metabolic Indicators at a Tertiary Hospital in Uganda

open access: yesDiabetes, Metabolic Syndrome and Obesity
Ritah Kiconco,1,2 Robert Kalyesubula,3,* Gertrude N Kiwanuka4,* 1Department of Medical Laboratory Science, Mbarara University of Science and Technology, Mbarara, Uganda; 2Department of Biochemistry, Soroti University, Soroti, Uganda; 3Departments
Kiconco R, Kalyesubula R, Kiwanuka GN
doaj  

Transition-Metal-Free Activation of Amide Bond by Arynes

open access: yesMolecules, 2018
Highly reactive arynes activate the N–C and C=O bonds of amide groups under transition metal-free conditions. This review highlights the insertion of arynes into the N–C and C=O bonds of the amide group.
Hideto Miyabe
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Thought Insertion Clarified. [PDF]

open access: yesJournal of consciousness studies : controversies in science & the humanities, 2015
'Thought insertion' in schizophrenia involves somehow experiencing one's own thoughts as someone else's. Some philosophers try to make sense of this by distinguishing between ownership and agency: one still experiences oneself as the owner of an inserted thought but attributes it to another agency.
Ratcliffe, M, Wilkinson, S
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Erasure Insertion in RS-Coded SFH MFSK Subjected to Tone Jamming and Rayleigh Fading

open access: yes, 2007
The achievable performance of Reed Solomon (RS) coded slow frequency hopping (SFH) assisted M-ary frequency shift keying (MFSK) using various erasure insertion (EI) schemes is investigated, when communicating over uncorrelated Rayleigh fading channels in
Ahmed, S, Yang, L-L, Hanzo, L
core  

On dynamic delay and repeater insertion. [PDF]

open access: yes, 2002
In deep sub-micron technologies, as the wires are placed ever closer and signal rise and fall times go into the sub-nano second region, increased crosstalk has implications on the data throughput and on signal integrity. Depending on the data correlation
Tenhunen, Hannu   +4 more
core   +1 more source

Deletion, insertion and translocation of DNA sequences contribute to chromosome size polimorphism in Plasmodium berghei

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
Extensive chromosome size polymorphism in Plasmodium berghei in vivo mitotic multiplication. Size differences between homologous chromosomes mainly involve rearrangements in the subtelomeric regions while internal chromosomal regions are more conserved ...
Chris J. Janse, Barend Mons
doaj   +1 more source

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