Results 141 to 150 of about 8,402,321 (334)

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Insertion Loss of Suspended Decorative Cylinders

open access: yes, 1985
The acoustical insertion loss of linear arrays of equally spaced suspended cylinders was measured. Insertion loss values were obtained for a varied number of cylinders, angle of incidence, and tube spacing for both solid, and expanded metal cylinders ...
Bradley, J. S.
core  

Low complexity Erasure Insertion in RS-Coded SFH Spread-Spectrum Communications with Partial-Band Interference and Nakagami-$m$ Fading

open access: yes, 2002
—In this paper we propose two novel low-complexity, low-delay erasure insertion schemes, namely, the output threshold test (OTT) and joint maximum output and ratio threshold Test (MO-RTT). The employment of the OTT and MO-RTT is beneficial in the context
Yang, Lie-Liang, Hanzo, Lajos
core   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

open access: yesAging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara   +3 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

YOUNGSTERS INSERTION ON THE LABOUR MARKET. A COMPARATIVE ANALYSIS ROMANIA - EUROPEAN UNION [PDF]

open access: yes
The insertion of young people into the labor market represents an important issue amongst all the countries within the European Union and this process is studied differently from one country to another.
Dobre Mihaela Hrisanta
core  

An Integrated SEA–Deep Learning Approach for the Optimal Geometry Performance of Noise Barrier

open access: yesMachines
The escalating environmental noise pollution along urban rail transit corridors, exacerbated by rapid urbanization, necessitates innovative and efficient noise control measures. A comprehensive investigation was conducted that utilized field measurements
Hao Wu   +4 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Traumatic loss and spiritual crisis in adolescence

open access: yes, 2006
This article extends Grof‘s (1985, 1993,1998 & 2000) work on psycho-spiritual transformation by discussing whether adolescents can experience ‘spiritual emergency’ (SE).
Bray, Peter
core  

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

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