Results 81 to 90 of about 845,814 (307)
A Radio Frequency Non-reciprocal Network Based on Switched Low-loss Acoustic Delay Lines
, 2018 This work demonstrates the first non-reciprocal network based on switched low-loss acoustic delay lines. A 21 dB non-reciprocal contrast between insertion loss (IL=6.7 dB) and isolation (28.3 dB) has been achieved over a fractional bandwidth of 8.8% at a
Gao, Anming +5 more
core +1 more source
Fabrication and coupling to planar high-Q silica disk microcavities [PDF]
, 2003 Using standard lithographic techniques, we demonstrate fabrication of silica disk microcavities, which exhibit whispering-gallery-type modes having quality factors (Q) in excess of 1 million.
Armani, D. K. +3 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Insertion loss and misalignment tolerance in multimode tapered waveguide bends [PDF]
, 2008 Experimental measurements of laterally tapered multimode waveguide bends fabricated photolithographically on FR4 printed circuit board establish that the product of the mean insertion loss (in linear units) and the mean source misalignment tolerance is a
Papakonstantinou, I +2 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
THE INSERTION LOSS OF POROELASTIC PLATE SILENCERS IN A FLOW DUCT [PDF]
, 2008 Idealized silencers consisting of cavity-backed clamped porous elastic plates parallel to the direction of flow can result in low frequency attenuation of noise in the duct.
Aygun, Haydar
core +1 more source
Non-Reciprocal gain in non-Hermitian time-Floquet Systems [PDF]
, 2017 We explore the unconventional wave scattering properties of non-Hermitian systems in which amplification or damping are induced by time-periodic modulation.
Fleury, Romain +1 more
core +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source