Results 91 to 100 of about 14,687,015 (226)

Evaluation of the I-gel, a supraglottic airway device in children undergoing day care surgery

Medical Journal of Dr. D.Y. Patil University, 2015
Background: The i-gel is a novel supraglottic airway device, made up of medical grade thermoplastic elastomer. Its soft noninflatable cuff causes easier insertion, minimal tissue compression and stability after insertion.
Sushma Raghunath Tandale, Nandini M Dave, Madhu Garasia   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Comparison of three different insertion techniques with LMA-UniqueTM in adults: results of a randomized trial

Revista Brasileira de Anestesiologia
Background The triple airway maneuver insertion technique allowed faster insertion of the LMA. This study compared three different insertion techniques of the laryngeal mask airway-UniqueTM.
Merih Eglen, Bahar Kuvaki, Ferim Günenç, Sule Ozbilgin, Semih Küçükgüçlü, Ebru Polat, Emel Pekel   +6 more
doaj   +1 more source

Ramped versus sniffing position for Ambu AuraGain insertion in patients with obesity: a randomized controlled study [PDF]

Korean Journal of Anesthesiology
Background The ramped position facilitates mask ventilation and endotracheal intubation in patients with obesity. This study aimed to determine whether the ramped position improves supraglottic airway (SGA) insertion in patients with obesity.
Hye-won Jeong, Hong-Beom Bae, Leyeoin Lee, Woojeong Lee, Joungmin Kim   +4 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

I-gel as an alternative to endotracheal tube in adult laparoscopic surgeries: A comparative study

Journal of Minimal Access Surgery, 2015
Background: The tracheal tube is always considered to be the gold standard for laparoscopic surgeries. As conventional laryngoscopy guided endotracheal intubation evokes significant hypertension and tachycardia, we have used I-gel, second generation ...
Jigisha Prahladrai Badheka, Rashida Mohammedi Jadliwala, Vrajeshchandra Amrishbhi Chhaya, Vandana Surendrabhai Parmar, Amit Vasani, Ajay Maganlal Rajyaguru   +5 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Comparison of Propofol and Sevoflurane for Laryngeal Mask Airway Insertion

Journal of Rawalpindi Medical College, 2013
Background: To compare the hemodynamic changes, conditions for the laryngeal mask airway (LMA) insertion and time of insertion between propofol and sevoflurane.
Ahmeduddin Soomro
doaj  

Assessment of Surgical Outcome of Trocar versus Blunt Dissection Technique for Intercostal Drainage Insertion: A Prospective Interventional Study [PDF]

International Journal of Anatomy Radiology and Surgery
Introduction: Chest tube insertion is a common procedure designed to alleviate the accumulation of air, fluid, pus, or blood in the pleural cavity. Despite being a bedside procedure often performed by emergency residents, Intercostal Drain (ICD) tube ...
Ashita Elizabeth Thomas, Anupama K Pujar, VR Anilkumar, Sreekar A Pai   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source