Results 141 to 150 of about 151,774 (262)

Deep Brain Stimulation and Pregnancy: A Case Report and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Verónica Cabreira, Maria José Rosas
wiley   +1 more source

Age and Nocturnal Polyuria in Nocturia: A Multicenter Voiding Diary Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Although the prevalence of nocturnal polyuria (NP) increases with age, the mechanisms underlying age‐related changes in voiding patterns and the daytime–nighttime distribution of urine volume remain unclear. Given that the severity of nocturia and bladder function may differ across age groups, age‐specific voiding profiles require
Kota Kawase, Yoshinori Nishino, Kanako Matsuoka, Shunta Makabe, Ryo Tanji, Hiroki Hoshino, Kei Kawada, Kousei Miwa, Masayuki Tomioka, Tomoki Taniguchi, Koji Iinuma, Yuki Tobisawa, Keita Nakane, Yoshiyuki Kojima, Takahiko Mitsui, Takuya Koie   +15 more
wiley   +1 more source

Peripheral and central immune features in insomnia: Integrative bulk and single-cell transcriptomic analyses reveal core hub genes and candidate compounds. [PDF]

Funct Integr Genomics
Zhu W, Wen Z, Gao Y, He B, Chen R, Pan H, Bin W, Yang Z, Tan F.   +8 more
europepmc   +1 more source

Circadian rhythms and chronotherapy in Alzheimer's disease: Mechanisms and therapeutic implications

Neuroprotection, EarlyView.
Circadian dysregulation contributes to Alzheimer's disease through sleep disruption, clock‐gene dysfunction, neuroinflammation, impaired proteostasis, and metabolic imbalance. These alterations promote cognitive decline and disease progression, while circadian biomarkers and chronotherapeutic interventions offer opportunities for precision diagnosis ...
Bivek Singh, Filippo Pigazzani, Roberto Manfredini   +2 more
wiley   +1 more source

Phenotypic Clues in Infantile‐Onset Parkinsonism‐Dystonia‐2: A Treatable Neurotransmitter Disorder

Movement Disorders Clinical Practice, EarlyView.
Sangeetha Yoganathan, Haya S. AlFaris, Lindsey Vogt, Michele Eid, Anika Menetrey, Sayoni Roy Chowdhury, Dawn Codeiro, Pradeep Krishnan, Liali Aljouda, Emily W.Y. Tam, Carolina Gorodetsky   +10 more
wiley   +1 more source

Efficacy and Safety of Electroacupuncture for Postoperative Insomnia in Patients With Spinal Metastasis: Protocol of a Prospective, Multicenter, Randomized Controlled Study. [PDF]

JMIR Res Protoc
Jiang C, Yin M, Peng X, Zhao J, Zhang F, Ma J, Wang D, Cao Y.   +7 more
europepmc   +1 more source

Distinct Symptom Occurrence Subgroups Among Patients With Colorectal Cancer: Differences in Social Determinants of Health and Diet Quality

Research in Nursing &Health, EarlyView.
ABSTRACT Colorectal cancer (CRC) is a leading cause of cancer mortality in the United States. Many patients with CRC experience physical and psychological symptoms that diminish quality of life and are shaped by social determinants of health (SDOH) and diet quality.
Youran Lee, Qing Yang, Melissa Kay, Donald E. Bailey, Biljana Gigic, Sheetal Hardikar, Adetunji T. Toriola, David Shibata, Christopher I. Li, Doratha A. Byrd, Jane C. Figueiredo, Ildiko Strehli, Megan Mclaws, Vaia Florou, Mmadili Ilozumba, Patricia Erickson, Apurva Medhe, Cornelia M. Ulrich, Rosa M. Gonzalez‐Guarda   +18 more
wiley   +1 more source

Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency

Obesity, EarlyView.
ABSTRACT Setmelanotide, a melanocortin 4 receptor (MC4R) agonist, is a promising pharmacological treatment option for people with rare monogenic obesity conditions affecting the leptin‐melanocortin signaling pathway, including proprotein convertase subtilisin/kexin type 1 (PCSK1) gene mutations.
Ellina Lytvyak, Arshdeep Rattol, Eduardo Grunvald   +2 more
wiley   +1 more source

Cognitive status moderates long-term benefits of non-pharmacological insomnia therapy in older adults: A secondary analysis of a randomized clinical trial. [PDF]

Alzheimers Dement
O'Hora KP, Morehouse AB, Hernandez B, Burda KF, Babros MC, Lazzeroni L, Zeitzer JM, Friedman L, Posner D, Kushida C, Manber R, Yesavage JA, Goldstein-Piekarski AN.   +12 more
europepmc   +1 more source

Impact of Life‐Context Factors on Chronic Rhinosinusitis 22‐Item Sinonasal Outcomes Test: Systematic Review + Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Chronic rhinosinusitis (CRS) affects all sociodemographic groups. While studies have explored social determinants of health (SDOH), sociodemographics, and health behaviors, their specific effects on CRS outcomes are unclear, making tailored care difficult.
Kassandra M. Jade, George A. Scangas, Victoria S. Lee, Li‐Xing Man, Edward D. McCoul, Gabriela Guevara, Anahita Nourmahnad, John M. Reynolds, Corinna G. Levine   +8 more
wiley   +1 more source